# Associate Director of Engineering at AstraZeneca

AstraZeneca is hiring an Associate Director of Engineering in Philadelphia, United States. Level rates it Little AI ●○○○; you can [apply on Level](https://jobsbylevel.com/go/a07225d9-9bae-4014-81fe-5767d6c76aa3).

AI Level 1, AI centrality 38 out of 100. US - Philadelphia - PA.

## Details

- Company: [AstraZeneca](https://jobsbylevel.com/companies/astrazeneca)
- AI level: AI Level 1 (score 38 out of 100)
- Location: US - Philadelphia - PA
- Posted: October 7, 2026
- Apply: https://jobsbylevel.com/go/a07225d9-9bae-4014-81fe-5767d6c76aa3

## Description

Introduction to the Role Are you ready to lead an engineering team that keeps critical manufacturing running flawlessly while modernizing how we deliver life-changing medicines? This role anchors a high-performing group at our Philadelphia site, resolving complex process issues in real time and driving strategic improvements across automation, aseptic manufacturing, packaging, and project execution. Your work will help ensure reliable supply, faster scale-up, and the quality our patients depend on. You will guide the selection and implementation of new and replacement systems, steward asset lifecycles, and bring data-driven, Lean thinking to a 24x7 GMP environment. Partnering closely with manufacturing, facilities, maintenance, IT, and quality functions, you will shape how we evolve our smart, sustainable production capabilities. How will you apply your automation and systems expertise to elevate performance and accelerate impact to patients? Accountabilities Team Leadership and Development: Lead a team of engineers with clear goals, coaching, and performance development. Build capability, foster accountability, and create a culture of openness where issues are raised early and solved at speed. System Selection and Lifecycle Ownership: Own the selection, design, and implementation of new and replacement systems for existing and tech transfer processes. Manage asset lifecycle decisions to improve reliability, throughput, and total cost of ownership. Issue Resolution and Root Cause: Resolve complex technical issues with equipment and automated systems by identifying root causes, defining corrective and preventive actions, and verifying effectiveness to sustain improvements. Change Control and Compliance: Lead change controls for equipment and automated systems, ensuring alignment with GMP, validation, data integrity, and SHE expectations. Positively reinforce standards, ensure training completion, and support audit readiness. Automation and Access Governance: Serve as System Administrator for production and facilities equipment, overseeing user access, audit trail reviews, data integrity checks, and preventive maintenance to ensure safe, secure, and compliant operations. Documentation and Training: Create and maintain operating procedures, maintenance instructions, and training materials that enable consistent, high-quality execution and rapid onboarding. Project and Portfolio Delivery: Plan and deliver projects on time and within budget, managing internal and external resources. Lead site-level coordination with IT and key stakeholders to integrate technology, reduce risk, and de-risk delivery. Lean and Continuous Improvement: Apply Lean concepts and waste reduction to enhance flow, availability, and quality. Use data analytics to identify bottlenecks, prioritize improvements, and measure impact. Cross-Functional Collaboration and Vendor Management: Partner with manufacturing, facilities, maintenance, quality, and IT. Guide procurement decisions and manage vendor and contractor performance to achieve outcomes and value. 24x7 Support Model: Ensure the right coverage and on-call support to sustain 24x7 operations, balancing responsiveness with preventive actions that reduce unplanned downtime over time. Ethical Leadership and Governance: Uphold the Code of Conduct, ensure team compliance with policies and standards, and provide the resources needed to maintain and continuously improve the Quality System. Essential Skills and Experience BA/BS in Engineering or Life Sciences. 10+ years of applicable experience. Experience in a manufacturing or packaging environment. Ability to communicate, manage people and projects, and lead and coach in a regulated environment. Project management skills and knowledge of change management processes. Knowledge of Good Manufacturing Practice, Safety, Health and Environment. Strong technical background in either Automation (OT), Mechanical Design, Electrical Design, or Process Development.

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/associate-director-of-engineering-at-astrazeneca-52d6ff

Source: https://jobsbylevel.com/jobs/associate-director-of-engineering-at-astrazeneca-52d6ff

## Cite this page

Level. https://jobsbylevel.com/jobs/associate-director-of-engineering-at-astrazeneca-52d6ff.

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