# Director, Cardiovascular and metabolic diseases, Clinical Pharmacology Modeling and Simulation at GSK

GSK is hiring a Director, Cardiovascular and metabolic diseases, Clinical Pharmacology Modeling and Simulation for a remote role open to applicants in United States. It pays $188k-$314k a year and Level rates it Little AI ●○○○; you can [apply on GSK](https://jobsbylevel.com/go/2b139416-d17e-4614-8c52-3edd577df06c?utm_medium=ai-agent).

AI Level 1, AI centrality 36 out of 100. Remote (USA - Massachusetts - Waltham).

## Details

- Company: [GSK](https://jobsbylevel.com/companies/gsk)
- AI level: AI Level 1 (score 36 out of 100)
- Location: Remote (USA - Massachusetts - Waltham)
- Salary: $188k-$314k
- Posted: October 29, 2026
- Apply: https://jobsbylevel.com/go/2b139416-d17e-4614-8c52-3edd577df06c?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=director-cardiovascular-and-metabolic-diseases-clinical-pharmacology-modeling-and-simulation-at-gsk-8cd940

## Description

Director, Cardiovascular and metabolic diseases, Clinical Pharmacology Modeling and Simulation For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029. The Department of Clinical Pharmacology Modelling & Simulation in Respiratory and Inflammation (CPMS R&I) at GSK is recruiting for a Director–level Clinical Pharmacologist with cardiovascular and metabolic disease expertise. This role sits within the newly established Clinical Pharmacology and Quantitative Medicine (CPQM) organisation, which aims to be a centre of excellence in Model‑Informed Drug Development (MIDD) by integrating clinical pharmacology, digital medicine, translational imaging and mechanistic/systems modelling. You will lead the end‑to‑end application of MIDD across the drug development lifecycle - from first‑in‑human studies through filing and lifecycle management - and provide clinical pharmacology strategy and evidence‑generation input. This is an opportunity to join a highly regarded, high‑impact team with a strong publication track record, reporting directly to the Respiratory, Immunology & Inflammation Research Unit (RIIRU). Main responsibilities and accountabilities include, but are not limited to: • Design & Execute Model Informed and Clinical Pharmacology strategies Develop and implement robust MIDD & ClinPharm evidence strategies to de risk and accelerate RIIRU programs. Aim for faster development, optimal dosing and stronger regulatory positioning across respiratory, inflammation, neurodegeneration and emerging areas — and support business development opportunities. • Ensure robust ways of working and regulatory ready evidence Draft and review clinical pharmacology regulatory content to support timely approvals and optimal labelling. Maintain up to date knowledge of FDA, EMA, CDE, PMDA and ICH expectations and embed regulatory considerations and best practices into study design and MIDD strategies. • Build cross functional partnerships Work closely with CPQM peers (digital medicine, translational imaging, MIDD specialists, mechanistic/systems modelling) and cross functional partners (biology, data science, computational biology, clinical, etc.). Maintain strong networks and share best practices in the CPMS community of practice. Build strong network key functions such as AI/ML, biomarkers, biostatistics, clinical operations, data science, computational biology and RWE to embed quantitative approaches into decision making at asset level. • External engagement & scientific leadership Raise GSK’s profile in MIDD, clinical pharmacology, QSP and AI/ML integration through publications, conference presentations and active participation in scientific and regulatory fora to influence method adoption and regulatory dialogue Why you? Basic Qualifications: We are looking for a professional with these required skills to achieve our goals: • PhD, MD, or PharmD • 5+ years of industry experience in clinical pharmacology, modelling/simulation and drug development to solve practical problems in pharmaceutical industry. • Experience in pharmacometrics and its application to clinical questions in drug development. Preferred Qualifications: • Experience in Cardiovascular and metabolic diseases. • Demonstrated experience of collaboration in a multi-disciplinary team, using effective communication and taking personal accountability for timely delivery of results. • Evidenced experience making sound judgement in complex situations and adapting to changing business needs by prioritizing multiple tasks. • Experience working with senior stakeholders in a cross functional environment. • Track record of implementation of Model-Informed Drug Discovery and

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/director-cardiovascular-and-metabolic-diseases-clinical-pharmacology-modeling-and-simulation-at-gsk-8cd940

Source: https://jobsbylevel.com/jobs/director-cardiovascular-and-metabolic-diseases-clinical-pharmacology-modeling-and-simulation-at-gsk-8cd940

## Cite this page

Level. https://jobsbylevel.com/jobs/director-cardiovascular-and-metabolic-diseases-clinical-pharmacology-modeling-and-simulation-at-gsk-8cd940.

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