# Director, Digital Twin & Intelligent Manufacturing Capabilities at AstraZeneca

AstraZeneca is hiring a Director, Digital Twin & Intelligent Manufacturing Capabilities. It pays $161k-$242k a year and Level rates it Little AI ●○○○; you can [apply on AstraZeneca](https://jobsbylevel.com/go/fee3e808-c888-478d-88dd-ee92db01bb35?utm_medium=ai-agent).

AI Level 1, AI centrality 7 out of 100. US - Gaithersburg - MD.

## Details

- Company: [AstraZeneca](https://jobsbylevel.com/companies/astrazeneca)
- AI level: AI Level 1 (score 7 out of 100)
- Location: US - Gaithersburg - MD
- Salary: $161k-$242k
- Posted: November 9, 2026
- Apply: https://jobsbylevel.com/go/fee3e808-c888-478d-88dd-ee92db01bb35?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=director-digital-twin-intelligent-manufacturing-capabilities-at-astrazeneca-c2fe15

## Description

Position Summary The Director, Digital Twin & Intelligent Manufacturing Capabilities is responsible for defining and advancing the enterprise strategy, technology direction, governance, standards, and capability roadmap for Digital Twins, Process Twins, Process Intelligence, Modeling, Simulation, Automation-enabled Manufacturing, and AI-driven manufacturing capabilities across Global Technical Operations (GTO). This role serves as GTO's enterprise leader for Digital Twin and Process Intelligence capabilities and is accountable for shaping how manufacturing science, process knowledge, automation, data, advanced analytics, artificial intelligence, and digital technologies are leveraged to improve technology transfer, process understanding, manufacturing readiness, operational performance, and business outcomes across the product lifecycle. The Director will partner closely with MPAS, Tech Transfer, BPD, Singapore manufacturing and digital organizations, Alexion, FMC, Regional Digital Leads, Manufacturing, IT, Enterprise Architecture, Data & AI, Automation, and Site Digital teams to establish enterprise-scale capabilities and implementation frameworks that can be deployed consistently across the manufacturing network. While Regional Digital Leads and site organizations retain accountability for site-level deployment and adoption, this role is responsible for defining the enterprise capability strategy, technology direction, operating model, governance, standards, and reusable assets required to scale Digital Twin and Process Intelligence capabilities across GTO. This position requires deep expertise in Digital Twin and Intelligent Manufacturing capabilities, combined with strong technology leadership, manufacturing and process-science credibility, automation awareness, systems thinking, vendor evaluation experience, AI and advanced analytics fluency, and a proven ability to lead large-scale cross-functional transformation initiatives in complex global organizations. Key Responsibilities Enterprise Strategy & Capability Leadership Define and maintain the enterprise strategy for Digital Twins, Process Twins, Process Intelligence, Modeling, Simulation, and Intelligent Manufacturing capabilities across GTO. Establish and evolve a multi-year capability roadmap aligned with GTO priorities, Digital Tech Transfer strategy, manufacturing modernization initiatives, and enterprise digital objectives. Identify strategic opportunities to improve technology transfer, process characterization, scale-up, manufacturing readiness, process robustness, operational performance, and business value. Develop capability maturity models, adoption frameworks, and value realization approaches to support enterprise scaling. Translate business needs and manufacturing challenges into actionable capability roadmaps, standards, investment priorities, and implementation approaches. Technology, Automation & Intelligent Manufacturing Leadership Define how Digital Twins, manufacturing systems, automation environments, process data, simulation platforms, advanced analytics, machine learning, and AI capabilities work together as part of GTO’s Intelligent Manufacturing ecosystem. Lead evaluation and selection of Digital Twin, Process Intelligence, Modeling, Simulation, and AI-enabled manufacturing technologies. Drive technology strategy and investment recommendations across platforms, tools, vendors, and strategic partnerships. Assess emerging technologies and industry developments to guide future capability investments and roadmap decisions. Partner with Enterprise Architecture, IT, Data & AI, Automation, and Digital organizations to define scalable architectures, integration approaches, and operational models. Establish approaches for connecting process knowledge, manufacturing systems, automation platforms, process data, simulations, and Digital Twins through effective data flows and information architectures. Guide build-versus-buy decisions and strategic

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/director-digital-twin-intelligent-manufacturing-capabilities-at-astrazeneca-c2fe15

Source: https://jobsbylevel.com/jobs/director-digital-twin-intelligent-manufacturing-capabilities-at-astrazeneca-c2fe15

## Cite this page

Level. https://jobsbylevel.com/jobs/director-digital-twin-intelligent-manufacturing-capabilities-at-astrazeneca-c2fe15.

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