# Director, Oncology Translational Medicine, Clinical Biomarkers at GSK

GSK is hiring a Director, Oncology Translational Medicine, Clinical Biomarkers for a remote role open to applicants in United States. It pays $190k-$316k a year and Level rates it Little AI ●○○○; you can [apply on GSK](https://jobsbylevel.com/go/0e57d70a-e7d6-4f4f-8cbe-5190d4b972f9?utm_medium=ai-agent).

AI Level 1, AI centrality 0 out of 100. Remote (USA - Pennsylvania - Upper Providence).

## Details

- Company: [GSK](https://jobsbylevel.com/companies/gsk)
- AI level: AI Level 1 (score 0 out of 100)
- Location: Remote (USA - Pennsylvania - Upper Providence)
- Salary: $190k-$316k
- Posted: October 26, 2026
- Apply: https://jobsbylevel.com/go/0e57d70a-e7d6-4f4f-8cbe-5190d4b972f9?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=director-oncology-translational-medicine-clinical-biomarkers-at-gsk-b3b02b

## Prepare for this job

The job page lists 4 likely interview questions for this offer, with a CV checklist: https://jobsbylevel.com/jobs/director-oncology-translational-medicine-clinical-biomarkers-at-gsk-b3b02b

## Description

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage, UK. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029. Director, Oncology Translational Medicine, Clinical Biomarkers Job Purpose: The Director, Oncology Translational Medicine, Clinical Biomarkers is responsible for the development and effective implementation of biomarker and translational medicine strategies to support the clinical development of late-stage oncology assets. As a key member of a Clinical Matrix Team (CMT), the Clinical Biomarker Director will collaborate with the Clinical Biomarker Executive Director to establish clear decision-making criteria, define patient segmentation strategies, and integrate these into clinical development plans. You will leverage cutting-edge technologies and methodologies to discover and clinically validate biomarkers, ensuring the biomarker strategy is fully aligned with the clinical plan. This integration will optimise decision-making in drug development and enable the identification of the right patient populations for our medicines. Key responsibilities: Collaborating closely with the Clinical Biomarker Executive Director to drive the design, alignment, and execution of clinical biomarker and translational medicine strategies focused on identifying predictive biomarkers that enable clinical success. Validating and implementing biomarker strategies, including target engagement, pharmacodynamic, and proof-of-mechanism biomarkers, for clinical-phase programs to support patient stratification, dose selection, and enable clinical go/no-go decisions. Participating in tumor-specific Biomarker Matrix teams, with responsibility for executing clinical biomarker strategies for late-stage oncology programs, while working closely with internal and external stakeholders, as well as disease area strategy teams. Representing Translational Medicine at Clinical Development Matrix Teams (CMT) to establish biomarker-driven decision-making criteria and their seamless integration into clinical study designs, aligning with clinical study objectives Supporting disease area strategies and translational objectives by defining biomarker priorities, areas of interest, and generating decision-enabling evidence packages informed by real-world datasets, internal and external data and partnerships (For e.g., research collaborations, KEE consultations). Identifying cutting-edge science and technological advances to incorporate into biomarker strategies for guiding indication selection, patient enrichment, and combination strategies. Overseeing and/or developing sample testing plans and delivering high-quality biomarker data packages to inform clinical development and regulatory strategies. Managing effective relationships with clinical and scientific operations, diagnostics, medical science, medical affairs, regulatory, portfolio management, and commercial functions. Supporting the expansion of mechanism and disease understanding to generate insights for indication expansion and scientific exchange as needed. Defining and studying mechanisms of resistance to enable reverse translation, inform next-line strategies, support patient enrichment, and influence life cycle management of assets. Contributing to the company’s scientific credibility through publications and presentations. Why You? Basic Qualifications: We are looking for professionals with the following required skills and experience: Ph.D. or equivalent with 7+ years or M.Sc. with 10+ years of drug development experience in the pharmaceutical industry , with a solid background in Oncology clinical biomarkers, expertise in late-phase oncology studies, and translational research within clinical development. Strong expertise in cancer

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Source: https://jobsbylevel.com/jobs/director-oncology-translational-medicine-clinical-biomarkers-at-gsk-b3b02b

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