# Director, Quantitative Systems Pharmacology at GSK

GSK is hiring a Director, Quantitative Systems Pharmacology for a remote role open to applicants in United States. It pays $188k-$314k a year and Level rates it Little AI ●○○○; you can [apply on Level](https://jobsbylevel.com/go/623098a7-b839-40f3-acbc-0b867700553a?utm_medium=ai-agent).

AI Level 1, AI centrality 32 out of 100. Remote (USA - Pennsylvania - Upper Providence).

## Details

- Company: [GSK](https://jobsbylevel.com/companies/gsk)
- AI level: AI Level 1 (score 32 out of 100)
- Location: Remote (USA - Pennsylvania - Upper Providence)
- Salary: $188k-$314k
- Posted: October 12, 2026
- Apply: https://jobsbylevel.com/go/623098a7-b839-40f3-acbc-0b867700553a?utm_medium=ai-agent

## Description

Business Introduction At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together. Find out more: Our approach to R&D Director, Quantitative Systems Pharmacology For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029. The Department of Clinical Pharmacology and Quantitative Medicine (CPQM) in the GSK Respiratory, Immunology and Inflammation Research Unit is recruiting for a Quantitative Systems Pharmacologist Lead. At GSK, CPQM is a newly established organization with the remit to become a Centre of Excellence in Model-Informed Drug Development (MIDD). It uniquely integrates clinical pharmacology, digital medicine, translational imaging, and mechanistic & systems modeling. The convergence of science and technology is changing discovery and development at GSK, allowing us to make advances on behalf of patients that were once thought impossible. Our R&D organization is delivering more innovation, better and faster, using new data and platform technologies that speed up discovery and development and improve the chance of success. This position represents a key opportunity for professionals with PhD, MD, or PharmD, who are experienced mechanistic modelers with experience in QSP and/or QST modeling, clinical pharmacology and pharmacometrics, to join the Quantitative Systems Pharmacology team to advance the vision and mission of GSK’s rapidly expanding Respiratory, Inflammation and Immunology Disease portfolio. Sought after experiences for this position include building mechanistic mathematical models and leveraging knowledge in the areas of scientific ML, inverse problems, AIML and/or statistical methodologies, to enhance the robustness and quality of model development to leverage for decision-making from exploratory research through clinical development. You will be expected to play a critical role in the day-to-day driving integration of end-to-end model-informed drug discovery and development through building and applying mechanistic QSP and QST models. In addition, you will be defining, implementing and coordinating QSP and QST related Clinical Pharmacology and Quantitative Medicine development strategies for disease and therapeutics of interest, and providing expert input into the clinical pharmacology evidence generation and integrated evidence plans in the Disease therapeutic area. This is an exciting opportunity to bring your vision and leadership to a new era of digital innovation in clinical pharmacology and quantitative medicine, profoundly impacting patient outcomes and shaping the future of R&D at GSK. Main responsibilities and accountabilities also include: · Build and/or guide mathematical model development to understand disease, its progression, and drug action to prevent, treat and cure diseases; conduct simulations to assess trial design performance · Apply mechanistic models of biological, physiological, and pathophysiological processes to evaluate a disease, its pathways and progression, as well as drug candidates or treatment modalities · Develop and/or utilize state-of-the-art mathematical tools including knowledge of

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