# Medical Ethics Manager - Alexion at AstraZeneca

AstraZeneca is hiring a Medical Ethics Manager - Alexion in London, United Kingdom. Level rates it Little AI ●○○○; you can [apply on AstraZeneca](https://jobsbylevel.com/go/c5e1fd76-f7c9-4942-9a90-26a2ece52bd7?utm_medium=ai-agent).

AI Level 1, AI centrality 33 out of 100. UK - London.

## Details

- Company: [AstraZeneca](https://jobsbylevel.com/companies/astrazeneca)
- AI level: AI Level 1 (score 33 out of 100)
- Location: UK - London
- Posted: October 27, 2026
- Apply: https://jobsbylevel.com/go/c5e1fd76-f7c9-4942-9a90-26a2ece52bd7?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=medical-ethics-manager-alexion-at-astrazeneca-67fa8f

## Description

Role: Medical Ethics Manager - Alexion Location: St Pancras London UK Salary: Competitive + Excellent Benefits Purpose: The Medical Ethics Manager enables the Alexion UK & Ireland Rare Disease business to deliver innovative, patient-centred activities in line with applicable Codes, legislation and company standards. Acting as a Nominated Signatory and trusted cross-functional partner, the role provides pragmatic, evidence-based advice that protects patients, scientific integrity and company reputation. The role also operationalises the Medical Ethics strategy by strengthening review processes, capability and insight, including the responsible use of approved AI-enabled tools to improve quality, consistency and cycle time. Key Responsibilities and Accountabilities Deliver high-quality, pragmatic medical ethics and Code support for Alexion UK & Ireland Rare Disease, enabling innovation while protecting patients, scientific integrity and company reputation. Act as Nominated Signatory for agreed promotional and non-promotional materials, activities and meetings, with accountability for cross-portfolio work and therapy-area support according to priorities. Operationalise the Medical Ethics Lead’s strategy, governance framework and annual book of work through review, advice, training, process management and continuous improvement. Use approved AI-enabled tools to improve review quality, consistency, insight and cycle time, with meaningful human oversight, source validation and protection of confidential, personal and proprietary information. Build understanding of Alexion’s rare disease portfolio, specialist care pathways and stakeholder needs alongside the ABPI/IPHA Codes, applicable legislation and internal standards. Nominated Signatory & Rare Disease Business Partnering (50%) Complete timely, accurate and pragmatic review and approval in line with the ABPI/IPHA Codes, applicable legislation and Alexion standards. Maintain current knowledge of Alexion’s rare disease portfolio, pipeline, specialist services and patient pathways. Partner across functions to enable scientifically robust, patient-centred and compliant solutions. Provide advice within established guidance and escalate novel, high-risk or precedent-setting questions. Coordinate approved third-party signatory support where allocated. Support complaint responses under the Medical Ethics Lead’s direction; do not independently own PMCPA complaints. AI-enabled Review, Process Management & Improvement (25%) Maintain and apply review procedures, checklists, guidance and operational controls under the Medical Ethics Lead’s governance. Identify AI use cases across triage, review preparation, claims and reference checks, consistency checks, trend analysis, knowledge retrieval and reporting. Use only approved AI tools and apply meaningful human review, checking accuracy, evidence quality, bias, missing context and unintended consequences. Work with Digital/Ops, Privacy, Legal, Compliance and Information Security on controlled pilots, adoption and feedback loops. Use review data and AI-supported pattern detection to identify recurring issues, training needs, bottlenecks and standardisation opportunities. Compliance Capability, Training & Insight (15%) Deliver training on SOPs, Codes, review standards and responsible AI use for the Alexion rare disease business. Support coaching, mentoring, validation and revalidation as delegated. Translate review trends into targeted guidance and learning. Model ethical, professional and patient-centred decision-making. Operational Delivery & Reporting (10%) Maintain effective information flow across Medical Ethics, signatories, third-party support and stakeholders. Maintain records and dashboards covering volumes, cycle times, themes, training and improvements. Provide updates and recommendations to the Medical Ethics Lead and escalate delivery risks. Essential Requirements: Registered Physician or Pharmacist eligible to act as a Nominated

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Source: https://jobsbylevel.com/jobs/medical-ethics-manager-alexion-at-astrazeneca-67fa8f

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Level. https://jobsbylevel.com/jobs/medical-ethics-manager-alexion-at-astrazeneca-67fa8f.

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