# Principal P&C Platform Architect - M365 at GSK

GSK is hiring a Principal P&C Platform Architect - M365 in London, United Kingdom. Level rates it Little AI ●○○○; you can [apply on GSK](https://jobsbylevel.com/go/59979d80-a1b7-4ea9-a11a-f7fe2cf97e43?utm_medium=ai-agent).

AI Level 1, AI centrality 34 out of 100. Remote (UK – London – New Oxford Street).

## Details

- Company: [GSK](https://jobsbylevel.com/companies/gsk)
- AI level: AI Level 1 (score 34 out of 100)
- Location: Remote (UK – London – New Oxford Street)
- Posted: October 20, 2026
- Apply: https://jobsbylevel.com/go/59979d80-a1b7-4ea9-a11a-f7fe2cf97e43?utm_medium=ai-agent

## Description

At GSK, we unite science, technology and talent to get ahead of disease together. We are a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together. We’re proud to be leading a healthcare revolution, and we’re looking for people who can help us deliver on our ambition. Role Overview Own the architecture of the platform where 50,000+ employees across multiple countries actually do their work — email, files, meetings, chat, intranet, workflow and, increasingly, AI assistance. This role is the definitive technical authority for the Microsoft 365 estate: Exchange Online, SharePoint Online, OneDrive, Teams, Viva, Power Platform, Microsoft 365 Copilot, and the Entra ID and Purview controls that govern them. Microsoft 365 is no longer a set of applications; it is a tenant-wide platform where an identity decision, a sharing default or a licensing choice propagates instantly to every user and every document. The Principal Platform Architect is accountable for making those decisions deliberately and coherently — balancing collaboration velocity against information protection, and platform capability against cost. This is a hands-on-capable role. The expectation is to build, prove and pressure-test designs in a lab tenant personally, and to be the person who understands what a setting actually does rather than what the documentation claims. In this role you will Own the target-state architecture for the M365 tenant: workload topology, tenant and domain strategy, identity and licensing model, data residency, and the integration surface with the wider application estate. Define the multi-year productivity and collaboration roadmap — workload adoption and retirement, migration off legacy platforms (on-premises Exchange/SharePoint, file shares, third-party collaboration tools), and consolidation of overlapping tooling. Track the Microsoft 365 roadmap and message centre continuously; assess incoming change for risk and opportunity, and decide what the organisation adopts, defers, or disables — before Microsoft decides for you. Produce and maintain reference architectures, design patterns and architecture decision records (ADRs) with trade-offs made explicit. Architect information protection across the tenant: Microsoft Purview sensitivity labels, retention and records management, DLP, eDiscovery, insider risk, and Communication Compliance. Design the external sharing, guest access and B2B collaboration model — the single most consequential and most frequently mis-set area of the platform. Ensure the tenant meets regulatory obligations: data privacy (GDPR and equivalents), data residency and Multi-Geo, GxP and validated-system requirements, records retention, legal hold, and audit/SOX ITGC evidence generation designed in rather than bolted on. Partner with Cyber Security on tenant security posture — Conditional Access, Defender for Office 365, Defender for Cloud Apps, Secure Score, token and session controls, and the endpoint's role in tenant trust. Own the architecture for Microsoft 365 Copilot and agent platforms: readiness assessment, permission and oversharing remediation, semantic index behaviour, grounding and data boundaries, licensing strategy and measurable value realisation. Establish governance for Copilot Studio and agent creation — who may build, on what data, with what review and lifecycle. Set the position on AI data handling and prompt/response retention that Legal, Privacy and the Works Council will accept. Architect the Power Platform environment strategy: environment topology, data loss prevention policies, connector governance, ALM pipelines, and the boundary between citizen and professional development. Design the guardrails that let the business build safely without generating an unmanaged shadow estate. Act as design authority for all M365 tenant change; chair or sit on the architecture review board and hold veto on standards deviation. Set engineering

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/principal-p-c-platform-architect-m365-at-gsk-9786c2

Source: https://jobsbylevel.com/jobs/principal-p-c-platform-architect-m365-at-gsk-9786c2

## Cite this page

Level. https://jobsbylevel.com/jobs/principal-p-c-platform-architect-m365-at-gsk-9786c2.

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