# Principal Scientist, Biophysics/Biochemical DMTL Automation at Johnson & Johnson

Johnson & Johnson is hiring a Principal Scientist, Biophysics/Biochemical DMTL Automation. It pays €64k a year and Level rates it Little AI ●○○○; you can [apply on Johnson & Johnson](https://jobsbylevel.com/go/b2b40629-0de3-4740-bb7c-3681cc1f5d70?utm_medium=ai-agent).

AI Level 1, AI centrality 26 out of 100. Toledo, Spain.

## Details

- Company: [Johnson & Johnson](https://jobsbylevel.com/companies/johnson-johnson)
- AI level: AI Level 1 (score 26 out of 100)
- Location: Toledo, Spain
- Salary: €64k
- Posted: November 5, 2026
- Apply: https://jobsbylevel.com/go/b2b40629-0de3-4740-bb7c-3681cc1f5d70?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=principal-scientist-biophysics-biochemical-dmtl-automation-at-johnson-johnson-a3951a

## Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com . As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biological Research Job Category: Scientific/Technology All Job Posting Locations: Toledo, Spain Job Description: Principal Scientist, Biophysics/Biochemical DMTL Automation Function: Discovery Technologies & Molecular Pharmacology Location: Toledo, Spain Level: Principal Scientist (ST7) Role Overview: We are seeking an innovative, highly collaborative, and self-directed Senior Scientist to advance next-generation biophysical and biochemical capabilities supporting Design-Make-Test-Learn (DMTL) workflows across Discovery within Discovery Technologies and Molecular Pharmacology (DTMP). Based in Toledo, Spain, this role will generate and interpret high-quality Surface Plasmon Resonance (SPR) and biochemical data to guide decisions from hit identification through lead optimization. The successful candidate will develop innovative assays, implement automated workflows, and partner across chemistry, biology, computational sciences, automation, and platform teams to accelerate DMTA cycles and strengthen the speed, quality, and predictability of discovery. Key Responsibilities: Biophysical and Biochemical Assay Development & Discovery Support Design, develop, and execute SPR and biochemical assays to support hit validation and lead optimization across discovery programs Generate and interpret kinetic, affinity, thermodynamic, and biochemistry data to guide SAR and critical project decisions DMTA Acceleration & Data Generation Deliver high-quality biophysical and biochemistry data that accelerates DMTL cycles and enables rapid, data-driven discovery decisions Develop robust and scalable experimental workflows that expand throughput and reproducibility across the portfolio Technology Innovation & Automation Drive the development and implementation of automated biophysical and biochemical lab design and workflows that increase experimental scale, consistency, and scientific impact Partner with automation, informatics, engineering, and platform teams across teams to integrate biophysical and biochemical capabilities into scalable DMTA workflows and next-generation discovery platforms Scientific Collaboration & Technical Leadership Act as an independent scientist, identifying opportunities, solving complex technical challenges, and leading cross-functional Discovery project teams to shape biophysical and biochemical strategies that advance project objectives Collaborate across chemistry, biology, computational sciences, structural biology, automation, and data science within Global Discovery Chemistry (GDC) and DTMP to translate biophysical and biochemical insights into portfolio decisions Qualifications Education • Ph.D. in Biophysics, Biochemistry, Structural Biology, or a related scientific discipline Required Experience & Skills • 8+ years of experience developing and executing biophysical and biochemical assays in a pharmaceutical, biotechnology, or academic research environment • Demonstrated hands-on expertise with SPR, complementary biophysical platforms, and biochemical techniques • Demonstrated ability to determine robust binding affinities

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/principal-scientist-biophysics-biochemical-dmtl-automation-at-johnson-johnson-a3951a

Source: https://jobsbylevel.com/jobs/principal-scientist-biophysics-biochemical-dmtl-automation-at-johnson-johnson-a3951a

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