# Principal Technical Program Manager, PXT Central Science at Amazon

Amazon is hiring a Principal Technical Program Manager, PXT Central Science in Seattle, United States. It pays $177k-$239k a year and Level rates it Little AI ●○○○; you can [apply on Amazon](https://jobsbylevel.com/go/3ff97042-e116-4630-9218-9bc74ec18d86?utm_medium=ai-agent).

AI Level 1, AI centrality 30 out of 100. US, WA, Seattle.

## Details

- Company: [Amazon](https://jobsbylevel.com/companies/amazon)
- AI level: AI Level 1 (score 30 out of 100)
- Location: US, WA, Seattle
- Salary: $177k-$239k
- Posted: November 10, 2026
- Apply: https://jobsbylevel.com/go/3ff97042-e116-4630-9218-9bc74ec18d86?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=principal-technical-program-manager-pxt-central-science-at-amazon-2d6ca1

## Description

We are seeking a Principal Technical Program Manager to drive complex, cross-team measurement-science initiatives from definition through delivery. This is a high-impact, high-autonomy role for someone who thrives in ambiguity, can create structure where none exists, and can force-multiply across many teams and organizations to land significantly complex technical programs. This is a technical program role that demands technical depth in science and software engineering. You will bring strong, data-driven judgment about the statistical systems that power employee listening, using that judgment to frame trade-offs, sequence delivery, and keep significantly complex scientific programs on track across teams. As our senior technical program leader, you will operate with complete independence across the Corporate, Worldwide Operations, and cross-cutting portfolios. You will drive program delivery where the business and methodological strategy has not yet been defined — working from research questions and methodology owned by science leadership, and orchestrating the science, engineering, and business teams required to deliver them at scale. You will advise VPs and senior leaders on program status, risks, and trade-offs. Key job responsibilities Cross-Team Technical Program Delivery • Own the delivery lifecycle of significantly complex, cross-team measurement-science programs — from requirements and sequencing through delivery, iteration, and long-term sustainability. • Force-multiply across science, engineering, and business teams, aligning many contributors toward coherent delivery of programs that no single team owns end to end. • Drive delivery in ambiguous, novel problem spaces where methodological and business strategy has not yet been defined, creating structure and a path forward where none exists. Science-Systems Technical Judgment • Bring deep, data-driven judgment about the measurement-science systems that power employee listening — sampling, weighting, instrument pipelines, and statistical methods — to frame technical trade-offs and identify delivery risks. Expertise is expected in measurement science, not software engineering. • Identify risks and opportunities in measurement-science strategies and the systems that implement them, driving simplification and efficiency across complex, interdependent scientific programs. • Recognize when a program needs additional scientific guidance and engage science leadership or subject-matter experts at the right moments. Science Partnership & Translation • Partner with research scientists to understand research questions and methodology, and translate them into cross-team technical program plans, sequencing, and delivery milestones. • Independently author accurate, decision-driving documents for senior leadership, including program plans, technical narratives, and launch reviews. Accuracy is non-negotiable: errors in how the science is represented undermine both trust and program integrity. Stakeholder Engagement & Influence • Build and maintain trusted relationships across PXT LT organizations, representing measurement-science programs. • Influence organizational priorities, resource allocation, and technical direction across teams and VP organizations without direct authority — aligning diverse teams toward simple, coherent approaches. • Manage escalations (is escalated to), proactively driving program and senior-leader reviews that surface risks, opportunities, and trade-offs clearly. Business Expansion & New Populations • Drive the technical program delivery required to extend measurement science to new business expansions, including Whole Foods Market, One Medical, Last Mile/Middle Mile, and future workforce populations. • Ensure new populations are integrated into the measurement framework without degrading existing program quality or scientific standards. Process Improvement & Automation • Identify and drive automation and process improvement across measurement-science

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/principal-technical-program-manager-pxt-central-science-at-amazon-2d6ca1

Source: https://jobsbylevel.com/jobs/principal-technical-program-manager-pxt-central-science-at-amazon-2d6ca1

## Cite this page

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