# Process Modelling & Simulation Lead – Synthetic Molecules Technical Development at Roche

Roche is hiring a Process Modelling & Simulation Lead – Synthetic Molecules Technical Development in Basel, Switzerland. Level rates it Little AI ●○○○; you can [apply on Roche](https://jobsbylevel.com/go/f084df2e-9212-4745-bdb7-5495bb22aa7b?utm_medium=ai-agent).

AI Level 1, AI centrality 20 out of 100. Basel.

## Details

- Company: [Roche](https://jobsbylevel.com/companies/roche)
- AI level: AI Level 1 (score 20 out of 100)
- Location: Basel
- Posted: October 29, 2026
- Apply: https://jobsbylevel.com/go/f084df2e-9212-4745-bdb7-5495bb22aa7b?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=process-modelling-simulation-lead-synthetic-molecules-technical-development-at-roche-8edb9e

## Prepare for this job

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## Description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted, and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop, and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Opportunity Lead the Modelling & Simulation Centre of Excellence (CoE): Define the strategy, vision, roadmap, standards, and governance for M&S across Synthetic Molecules Technical Development (PTDC), matrix-leading a cross-departmental community of 20+ experts around shared organizational priorities. Drive Strategic Alignment & Leadership: Influence and guide senior leaders across an organization of 700+ employees, proposing innovative ways of working, prioritizing high-impact applications, and serving as a key cross-functional connector without direct formal authority. Shape End-to-End M&S Strategy: Identify where mechanistic, hybrid, and data-driven modelling deliver maximum impact across both Drug Substance and Drug Product lifecycles—from early lab development through scale-up, technology transfer, and commercial manufacturing. Deliver High-Impact Process Solutions: Act as the senior technical authority on complex development challenges, leveraging chemical engineering principles to optimize processes, support experimental design, refine scale-up/scale-down models, and support regulatory submissions. Build Reusable Digital Capabilities: Spearhead the creation of validated model libraries, digital twins, scale-up tools, and self-service applications to establish consistent, scalable modelling standards and reduce duplicated effort across project teams. Drive Organizational Capability & Literacy: Coach and mentor scientists and engineers, elevating M&S literacy across project teams while fostering seamless collaboration between domain experts, modellers, data scientists, and technical partner functions. Connect Roche with External Innovation: Establish external partnerships with universities, research consortia, and technology vendors to evaluate emerging scientific advances and integrate cutting-edge M&S methodologies into the organization. Manage Hardware & Software Strategy: Influence high-value technology investments and vendor partnerships, maintaining governance and decision-making over a six-figure software portfolio. Who You Are Advanced Academic Foundation: Master’s degree or PhD in Chemical Engineering, Pharmaceutical Sciences, Chemistry, or a closely related discipline. Extensive Process & Modelling Leadership: 12+ years of professional experience in process engineering and M&S within the pharmaceutical or science-based industries, demonstrating deep technical expertise across end-to-end Drug Substance and Drug Product development. Proven Matrix Leadership & Stakeholder Influence: Demonstrated ability to lead complex initiatives across matrixed organizations, challenge the status quo, and align senior decision-makers across PTD and R&D without relying on direct organizational authority to champion, advocate for, and bring visibility to M&S initiatives. Advanced Modelling & Programming Expertise: Hands-on experience with industry-standard modelling platforms (e.g., gPROMS/gWAP, Dynochem) and scientific programming languages (Python, MATLAB), combined with strong knowledge of scale-up/down

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/process-modelling-simulation-lead-synthetic-molecules-technical-development-at-roche-8edb9e

Source: https://jobsbylevel.com/jobs/process-modelling-simulation-lead-synthetic-molecules-technical-development-at-roche-8edb9e

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