# Senior Director, Operations IT – Strategy and Operational Excellence at AstraZeneca

AstraZeneca is hiring a Senior Director, Operations IT – Strategy and Operational Excellence. It pays $189k-$284k a year and Level rates it Uses AI ●●○○; you can [apply on Level](https://jobsbylevel.com/go/0fb03813-7533-4063-9966-cc1b62cf7e6e?utm_medium=ai-agent).

AI Level 2, AI centrality 45 out of 100. US - Gaithersburg - MD.

## Details

- Company: [AstraZeneca](https://jobsbylevel.com/companies/astrazeneca)
- AI level: AI Level 2 (score 45 out of 100)
- Location: US - Gaithersburg - MD
- Salary: $189k-$284k
- Posted: October 15, 2026
- Apply: https://jobsbylevel.com/go/0fb03813-7533-4063-9966-cc1b62cf7e6e?utm_medium=ai-agent

## Prepare for this job

The job page lists 5 likely interview questions for this offer, with a CV checklist: https://jobsbylevel.com/jobs/senior-director-operations-it-strategy-and-operational-excellence-at-astrazeneca-fcfd1c

## Description

Senior Director, Operations IT Strategy and Operational Excellence Introduction to role : Are you ready to turn data, AI and operational rigor into a performance engine that speeds life-changing medicines to patients? Can you cut through complexity to set the pace on strategy, governance and measurable outcomes across a global Operations technology landscape? In this role, you will lead the strategy execution and performance engine for Operations IT, aligning technology priorities with Operations objectives to raise efficiency, quality and delivery reliability. You will translate insight into clear investment choices, strengthen portfolio governance and embed practical, responsible AI to improve analysis, decision-making and execution. You will join a technology function with the backing and investment to scale modern platforms in data, cloud and AI. You will partner closely with senior leaders across Operations, Finance and HR to turn evidence into decisions and decisions into results—helping our enterprise become truly digital and data-led. Accountabilities: Performance and Outcomes: Establish a disciplined performance rhythm across Operations IT, aligning governance and delivery for enterprise initiatives to clear roles, timelines and quality standards. Own the OKRs, KPIs and scorecard; interrogate performance with analytical rigour; benchmark within and beyond the industry; and translate insights into actions that demonstrate measurable improvements in productivity, cost, quality and delivery. Strategy and Investment Clarity: Partner with the Operations IT leadership team to evolve strategy aligned to Operations priorities, long-term technology ambition and the company’s Bold Ambition. Structure ambiguous problems, evaluate options and trade-offs, and recommend evidence-based priorities. Define strategic landmarks, maintain capability roadmaps and facilitate medium-term planning and reporting with robust data and clear executive narratives. Operational Excellence and Data Integrity: Embed operational governance, standards and processes, so they are understood, adopted and effective. Ensure operational data—including the Configuration Management Database and project portfolio information—is accurate, maintained and decision-ready. Simplify processes, remove unnecessary complexity, and fix recurring issues through structured problem-solving. Use approved AI tools in daily workflows for information synthesis, data analysis, communications, leadership materials and appropriate task automation. Orchestrate leadership communications and partner engagement, deliver effective monthly Town Halls, and coordinate initiatives to realise defined outcomes. Lead employee engagement cycles as a Pulse Champion, converting insights into practical improvements. Portfolio Leadership and Value Realisation: Run end-to-end portfolio governance to drive strategic alignment, prioritisation and delivery to scope, time and quality. Maintain a single source of truth for portfolio health, actively manage risks, dependencies and change, and produce consistent dashboards and decision-ready narratives. Partner with Finance to set budgets, forecast and track spend, optimise investment allocation and benefits realisation, and uphold financial controls and funding guardrails. Use analytical insight to recommend where to invest, accelerate, simplify, reshape or stop activity, balancing business value, risk and capacity. Essential Skills/Experience: Bachelor’s degree or equivalent experience with a minimum of 10 years’ industry experience. - Strong critical thinking and structured problem-solving skills, with the ability to challenge assumptions, assess evidence, identify root causes and reach sound conclusions. - An analytical approach, with demonstrated ability to interpret sophisticated financial, workforce, operational and portfolio data and translate it into clear recommendations and action. - A proven track record of driving measurable results, taking

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/senior-director-operations-it-strategy-and-operational-excellence-at-astrazeneca-fcfd1c

Source: https://jobsbylevel.com/jobs/senior-director-operations-it-strategy-and-operational-excellence-at-astrazeneca-fcfd1c

## Cite this page

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