# Senior MES Platform Engineer (Manufacturing Execution System) at GSK

GSK is hiring a Senior MES Platform Engineer (Manufacturing Execution System) for a remote role open to applicants in United Kingdom. Level rates it Little AI ●○○○; you can [apply on GSK](https://jobsbylevel.com/go/556d3f75-85e0-41e6-b324-c00eab261ed6?utm_medium=ai-agent).

AI Level 1, AI centrality 36 out of 100. Remote (UK - Hertfordshire - Ware).

## Details

- Company: [GSK](https://jobsbylevel.com/companies/gsk)
- AI level: AI Level 1 (score 36 out of 100)
- Location: Remote (UK - Hertfordshire - Ware)
- Posted: November 11, 2026
- Apply: https://jobsbylevel.com/go/556d3f75-85e0-41e6-b324-c00eab261ed6?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=senior-mes-platform-engineer-manufacturing-execution-system-at-gsk-d59715

## Description

We are looking for a Technical Specialist ( Senior MES Platform Engineer) to join our Global Supply Chain (GSC) Digital and Technology function. The GSC Digital and Technology function spearheads the implementation of integrated digital solutions and AI into the supply chain (including Smart Manufacturing, Enterprise Resource Planning – ERP - Evolution and broader supply chain technology and data capabilities). Job Purpose: The Senior MES Platform Engineer provides technical expertise for the lifecycle, reliability, compliance and continuous evolution of global Manufacturing Execution System (MES) platforms and associated manufacturing data technologies. The role turns the technical roadmap and platform backlog into robust designs and executable delivery plans for upgrades, vendor releases, infrastructure changes, remediation and standardisation. It assesses technical options, defines reusable engineering patterns, reviews contractor designs and ensures that solutions are secure, scalable, validated, supportable and aligned with enterprise architecture and manufacturing technology standards. The position works across several platforms, including Siemens Opcenter, AspenTech manufacturing solutions, Emerson Syncade, and Aspen IP.21. Working closely with the Global MES Platform Manager, MES Platform Manager, Product Owners, Architects, Infrastructure and Cloud teams, Computer System Validation, Quality, Cyber Security, Service Management, vendors and delivery partners, the role provides hands-on technical leadership to coordinates complex engineering activities and lead technical troubleshooting. This includes ensuring effective documentation and knowledge transfer from external contractors to the internal organisation. Key Responsibilities (include..,): • Translate the MES technical roadmap and platform backlog into solution designs, engineering work packages, implementation plans and technical acceptance criteria. Manage technical assessment of vendor releases, patches, support requirements, infrastructure dependencies and obsolescence risks. • Design and review platform upgrades and major changes across application, database, operating system, integration and hosting layers. Define and maintain reusable platform configurations, engineering standards, reference patterns, installation approaches and technical documentation. • Provide senior engineering expertise across Azure, virtual machines, on-premises hosting, Windows Server, databases, networks, backup, recovery, monitoring and platform integrations. • Partner with Solution and Enterprise Architects to ensure designs are integrated, scalable, resilient, secure, supportable and aligned with enterprise standards. Work with Computer System Validation and Quality teams to assess validation impact and ensure that design, build, test and release evidence supports GxP, Good Automated Manufacturing Practice (GAMP) and applicable quality requirements. • Ensure platform changes follow required controls for cyber security, data protection, change management, service readiness, operational resilience and records management. • Manage technical delivery performed by contractors, system integrators and specialist suppliers, including design reviews, quality checks, issue resolution, documentation and knowledge transfer. Act as a technical interface with software vendors and delivery partners, challenge proposed solutions and clarify product behaviour, defects, limitations and upgrade requirements. • Manage complex troubleshooting across application and infrastructure layers, identify root causes and drive sustainable remediation. Support release planning, environment readiness, installation, configuration, testing, cutover, hypercare and transition into support. • Maintain visibility of technical risks, dependencies, technical debt, supportability and lifecycle status, and escalate material issues to the MES Platform Manager. • Coach the MES Platform Engineer and contractor resources,

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/senior-mes-platform-engineer-manufacturing-execution-system-at-gsk-d59715

Source: https://jobsbylevel.com/jobs/senior-mes-platform-engineer-manufacturing-execution-system-at-gsk-d59715

## Cite this page

Level. https://jobsbylevel.com/jobs/senior-mes-platform-engineer-manufacturing-execution-system-at-gsk-d59715.

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