# Senior Principal - AI ML and Cloud Security at GSK

GSK is hiring a Senior Principal - AI ML and Cloud Security for a remote role open to applicants in India. Level rates it Works on AI ●●●○; you can [apply on GSK](https://jobsbylevel.com/go/2c91caf5-2045-44b6-a2b0-becaa7962977?utm_medium=ai-agent).

AI Level 3, AI centrality 67 out of 100. Remote (Bengaluru Luxor North Tower).

## Details

- Company: [GSK](https://jobsbylevel.com/companies/gsk)
- AI level: AI Level 3 (score 67 out of 100)
- Location: Remote (Bengaluru Luxor North Tower)
- Posted: November 9, 2026
- Apply: https://jobsbylevel.com/go/2c91caf5-2045-44b6-a2b0-becaa7962977?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=senior-principal-ai-ml-and-cloud-security-at-gsk-fb29d6

## Prepare for this job

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## Description

GSK remains committed to achieving bold commercial ambitions for the future. By 2031, we aim to deliver £40 billion in annual sales, leveraging our existing strong performance momentum to significantly increase our positive impact on the health of billions of patients globally. Our Ahead Together strategy is centred on early intervention to prevent and alter the course of disease, thereby protecting people and supporting healthcare systems. Our diverse portfolio consists of vaccines, specialty medicines, and general medicines. Through continuous innovation and a dedicated focus on scientific and technical excellence, we strive to develop and launch new, groundbreaking treatments that address critical health challenges. Domain focus: AI Architecture & Standards (AI security standards, AI threat modelling and model/agent risk tiering). Job Purpose: Own the AI security standards library and the architecture governance framework for Cyber Architecture and Solutions.Own the AI security standards library and the architecture governance framework for Cyber Architecture and Solutions. This role owns standards and governance rather than solution design, which sits with AI Architecture. You run the quality reviews that confirm what Engineering built matches what Architecture specified, own the architecture decision log, and maintain the AI threat model library. The standards you write are binding on AI initiatives well beyond Cyber Architecture and Solutions. About the team : AI ML and Cloud Security is the function through which GSK is transforming security itself. The team designs and builds the agentic framework, a multi-agent platform moving security services across the Chief Security Office from rule-based to AI-driven operation. It owns AI architecture and AI engineering end to end: the agent layer, LLM orchestration, the AI and ML platform, and the data fabric pipeline that Cyber Architecture and Solutions designs, builds and tests before a managed service vendor operates it. The team also governs AI tool security posture, advises on cloud security across the Azure and GCP estate, and is the front door between GSK's business units and R&D and the technical AI function. AI security standards set here are binding on every AI initiative in GSK. Seventeen roles across the UK, India and the US. What makes this role different. This is the quality gate on GSK's AI work. It suits someone who writes with real precision and enjoys building the framework rather than shipping the feature — the value shows up as problems that never happened. You need enough hands-on AI depth to tell a genuine control from a plausible-sounding one, because vendors and internal teams will present both. If you want to be building agents, apply for the engineering roles instead. Key responsibilities: This role will provide you the opportunity to lead key activities to progress your career. These responsibilities include some of the following: Develop and maintain the AI security standards library and the architecture governance framework. Run architecture quality reviews validating that Engineering builds match approved specifications. Own the architecture decision log so design rationale stays traceable for audit and regulatory inspection. Build and maintain the AI threat model library: prompt injection including indirect, training data poisoning, model extraction, adversarial input, agent privilege escalation. Translate the EU AI Act, NIST AI RMF and ISO/IEC 42001 into practical architectural requirements rather than restating them. Define the governance gates an AI capability must pass before build, release or vendor handover. Hold office hours for the engineering teams and turn the three most-asked questions each quarter into new pattern guidance, so the same exception is not requested twice. Support assurance, audit and regulatory evidence requests from the governance framework. Re-baseline the standards library against each new OWASP Top 10 for LLM

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/senior-principal-ai-ml-and-cloud-security-at-gsk-fb29d6

Source: https://jobsbylevel.com/jobs/senior-principal-ai-ml-and-cloud-security-at-gsk-fb29d6

## Cite this page

Level. https://jobsbylevel.com/jobs/senior-principal-ai-ml-and-cloud-security-at-gsk-fb29d6.

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