# Senior Principal - Principal RE, Cloud & Hosting at GSK

GSK is hiring a Senior Principal - Principal RE, Cloud & Hosting for a remote role open to applicants in India. Level rates it Uses AI ●●○○; you can [apply on GSK](https://jobsbylevel.com/go/651994da-544b-4cd3-954d-dad8a71b9f32?utm_medium=ai-agent).

AI Level 2, AI centrality 45 out of 100. Remote (Bengaluru Luxor North Tower).

## Details

- Company: [GSK](https://jobsbylevel.com/companies/gsk)
- AI level: AI Level 2 (score 45 out of 100)
- Location: Remote (Bengaluru Luxor North Tower)
- Posted: October 27, 2026
- Apply: https://jobsbylevel.com/go/651994da-544b-4cd3-954d-dad8a71b9f32?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=senior-principal-principal-re-cloud-hosting-at-gsk-1779da

## Prepare for this job

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## Description

Business Introduction GSK remains committed to achieving bold commercial ambitions for the future. By 2031, we aim to deliver £40 billion in annual sales, leveraging our existing strong performance momentum to significantly increase our positive impact on the health of billions of patients globally. Our Ahead Together strategy is centred on early intervention to prevent and alter the course of disease, thereby protecting people and supporting healthcare systems. Our diverse portfolio consists of vaccines, specialty medicines, and general medicines. Through continuous innovation and a dedicated focus on scientific and technical excellence, we strive to develop and launch new, groundbreaking treatments that address critical health challenges. Job Purpose The Site Reliability Engineer improves the reliability, resilience and observability of GSK's platforms as a hands-on engineer, reducing toil, preventing incidents and meeting agreed reliability targets. The role defines and monitors SLOs, instruments platforms for observability, leads incident response through to permanent prevention, and applies AI and automation for anomaly detection, predictive alerting and self-healing. It also coaches platform engineering teams in reliability practice and error-budget discipline. The role sits in Reliability Engineering & Operations and is deployed into a platform domain while drawing on the central capability, so it holds the central reliability standard inside a team it does not report to. Platform build and engineering direction sit with the Principal Engineers and the Engineering Director, the major incident process sits with the Major Incident Manager, and the reliability standard itself is set by the Reliability Engineering Senior Director. Reliability targets are held jointly with the Platform Manager rather than imposed on them. ROLE SCALE AND COMPLEXITY This is a senior enterprise reliability leadership role operating across globally distributed, business-critical cloud and hosting services. The post holder is accountable for setting technical direction, resolving systemic and ambiguous reliability risks, and influencing prioritisation across multiple platform teams, suppliers and geographies without relying on direct line authority. The role manages a portfolio of interdependent services with material operational, regulatory, cyber, resilience and financial consequences. It shapes investment and supplier decisions and may influence or govern an annual technology and service portfolio of up to approximately GBP 23 million, where applicable to the assigned scope. MARKET SCOPE Global scope, supporting business operations across regions, countries and markets in which GSK operates. The role establishes consistent reliability outcomes across regional delivery teams while accommodating local regulatory, data-residency, business-continuity and market-criticality requirements. Key Responsibilities • Define and monitor SLOs for the platforms served, and instrument those platforms for observability so reliability is measured rather than assumed. • Apply AI and automation for anomaly detection, predictive alerting and self-healing, so that recurring conditions are handled without human intervention. • Lead incident response for the platforms served, and drive root-cause resolution through to permanent prevention rather than closing on restoration. • Improve resilience through capacity, failover and recovery engineering, and test recovery rather than documenting it. • Reduce operational toil through automation and reusable tooling, working the identified manual task and toil candidates and evidencing the effort removed. • Close observability coverage gaps for the platforms served, prioritising by the reliability risk each gap leaves unmeasured. • Coach platform engineering teams in reliability practice and error-budget discipline, so reliability is built in rather than inspected in. • Track reliability metrics against SLOs and team OKRs,

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Source: https://jobsbylevel.com/jobs/senior-principal-principal-re-cloud-hosting-at-gsk-1779da

## Cite this page

Level. https://jobsbylevel.com/jobs/senior-principal-principal-re-cloud-hosting-at-gsk-1779da.

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