# Senior Principal Scientist, Data Science - R&D DDSAI - Therapeutics Development & Supply (TDS) at Johnson & Johnson

Johnson & Johnson is hiring a Senior Principal Scientist, Data Science - R&D DDSAI - Therapeutics Development & Supply (TDS). It pays $137k-$236k a year and Level rates it Little AI ●○○○; you can [apply on Johnson & Johnson](https://jobsbylevel.com/go/a6da0336-fc40-4fe9-b502-ff2f9546e469?utm_medium=ai-agent).

AI Level 1, AI centrality 19 out of 100. Spring House, Pennsylvania, United States of America.

## Details

- Company: [Johnson & Johnson](https://jobsbylevel.com/companies/johnson-johnson)
- AI level: AI Level 1 (score 19 out of 100)
- Location: Spring House, Pennsylvania, United States of America
- Salary: $137k-$236k
- Posted: October 28, 2026
- Apply: https://jobsbylevel.com/go/a6da0336-fc40-4fe9-b502-ff2f9546e469?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=senior-principal-scientist-data-science-r-d-ddsai-therapeutics-development-supply-tds-at-johnson-johnson-51c331

## Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. Job Function: Data Analytics & Computational Sciences Job Sub Function: Data Science Job Category: Scientific/Technology All Job Posting Locations: Malvern, Pennsylvania, United States of America, Spring House, Pennsylvania, United States of America Job Description: Position Summary Therapeutics Development & Supply (TDS) bridges scientific discovery and clinical application across Chemistry, Manufacturing and Controls (CMC), device development, and clinical supply chain. The R&D Data, Data Science & AI (DDSAI) organization is seeking a Senior Principal Scientist, Data Science to lead the development and adoption of Operations Research and Decision Intelligence solutions across TDS. This is a senior individual technical contributor role combining hands-on modeling, technical leadership, and cross-functional influence. This role will work with senior stakeholders, Director- and VP-level, across TDS, aligning priorities, clarifying decision needs, and communicating recommendations, trade-offs, and risks. The role will develop reusable forecasting, optimization, simulation, and decision-modeling capabilities for portfolio and resource planning, business operations, laboratory and process digital twins, and clinical supply. A successful candidate has a strong background in Operations Research or Engineering and has experience in pharmaceutical CMC development or supply chain. Key Responsibilities Model Development & Decision Support Design, build, validate, and deliver forecasting, optimization, simulation, and decision-support solutions for complex scientific, planning, and operational problems. Develop long- and short-term portfolio, workload, resource, and capacity forecasts; quantify uncertainty, dependencies, and scenario sensitivities. Develop business operations analytics and laboratory or process digital twins that connect demand, workflow, equipment, capacity, and performance to actionable decisions. Apply operations research methods to clinical supply and development planning, making assumptions, trade-offs, and model limitations explicit. Technical Leadership & Sustainable Delivery Develop reusable modeling frameworks, reference implementations, and practical guidance for forecasting, mathematical optimization, simulation, decision analysis, and uncertainty quantification. Apply disciplined software and model-development practices, including modular code, version control, testing, documentation, reproducibility, peer review, sensitivity analysis, and monitoring. Partner with J&J Technology and DDSAI teams on data integration, deployment, observability, security, support, and lifecycle ownership; work with quality and compliance partners where regulated controls are required. Provide technical guidance and mentorship to data scientists and quantitative practitioners through problem formulation, model architecture, code review, and validation. Collaboration & Adoption Work with TDS scientists, engineers, laboratory leaders, Clinical Supply Chain, business operations, Digital Operations & Strategy, and Finance to define decision needs and embed solutions into established workflows. Collaborate with DDSAI data

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/senior-principal-scientist-data-science-r-d-ddsai-therapeutics-development-supply-tds-at-johnson-johnson-51c331

Source: https://jobsbylevel.com/jobs/senior-principal-scientist-data-science-r-d-ddsai-therapeutics-development-supply-tds-at-johnson-johnson-51c331

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Level. https://jobsbylevel.com/jobs/senior-principal-scientist-data-science-r-d-ddsai-therapeutics-development-supply-tds-at-johnson-johnson-51c331.

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