# Senior Principal Scientist Pharmacology at Johnson & Johnson

Johnson & Johnson is hiring a Senior Principal Scientist Pharmacology. Level rates it Little AI ●○○○; you can [apply on Johnson & Johnson](https://jobsbylevel.com/go/00f2c5d4-63f6-4f07-9110-fd051bb4040c?utm_medium=ai-agent).

AI Level 1, AI centrality 30 out of 100. Spring House, Pennsylvania, United States of America.

## Details

- Company: [Johnson & Johnson](https://jobsbylevel.com/companies/johnson-johnson)
- AI level: AI Level 1 (score 30 out of 100)
- Location: Spring House, Pennsylvania, United States of America
- Posted: November 2, 2026
- Apply: https://jobsbylevel.com/go/00f2c5d4-63f6-4f07-9110-fd051bb4040c?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=senior-principal-scientist-pharmacology-at-johnson-johnson-f79f9f

## Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com . As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. Please note that this role is available across multiple countries and may be posted under different requisition numbers to comply with local requirements. While you are welcome to apply to any or all of the postings, we recommend focusing on the specific country(s) that align with your preferred location(s): Belgium R-087821, United States of America R-108326 Remember, whether you apply to one or all of these requisition numbers, your applications will be considered as a single submission. Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Pharmacology Job Category: Scientific/Technology All Job Posting Locations: Spring House, Pennsylvania, United States of America Job Description: Position Title Senior Principal Scientist Pharmacology 3Rs Portfolio Innovation and External Engagement Location Beerse, Belgium or Spring House, US. Role Summary The Sr. Principal Scientist & SIS Scientific Lead is a senior scientific role within Scientific & In Vivo Strategies (SIS), responsible for driving the identification and enablement of 3Rs innovation opportunities into the discovery and preclinical portfolio, including new approach methodologies (NAMs). Operating within the enterprise 3Rs framework and aligned with Discovery, Product Development & Supply (DPDS), PSTS (Preclinical Safety and Translational Sciences), and SIS strategic priorities, this role brings deep NAMs expertise (i.e., refined in vivo , ex vivo , complex in vitro models (CIVMs)/microphysiological systems (MPS)/organoids, and/or in silico approaches) to enable portfolio‑relevant 3Rs innovation that strengthens discovery and preclinical assessment and improves preclinical-to-clinical translatability while advancing 3Rs objectives. The individual will serve as a NAMs subject‑matter expert for SIS, DPDS, and Therapeutic Area stakeholders, ensuring that both internal and external NAM opportunities are identified and evaluated through portfolio‑relevant, translational, and regulatory‑aligned perspectives. Primary Responsibilities: NAMs Scientific Engagement and Portfolio Integration: Engage with fellow SIS Scientific Leads and stakeholders to identify and evaluate ex vivo , in vitro , and in silico (in partnership with data science colleagues) NAM opportunities relevant to discovery and development programs Provide subject-matter expert-level guidance on applicability, strengths, limitations and readiness of NAMs within specific disease, modality and contexts of use Drive relevant incorporation of NAMs into program strategies, ensuring alignment with portfolio goals, scientific rigor and the broader enterprise 3Rs innovation framework External NAMs Landscape and Regulatory Awareness: Maintain active awareness of the external NAMs landscape, including academic advances, emerging platforms and biotech innovations Evaluate external NAM developments in the context of scientific maturity, translational relevance, and evolving global regulatory perspectives (e.g., FDA, EMA, ICH, etc.) Translate external and regulatory signals into clear, balanced scientific insights to inform on current NAMs integration opportunities as well as to anticipate

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Source: https://jobsbylevel.com/jobs/senior-principal-scientist-pharmacology-at-johnson-johnson-f79f9f

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