# Senior Scientist, Downstream Process Development R&D at Pfizer

Pfizer is hiring a Senior Scientist, Downstream Process Development R&D. It pays $94k-$156k a year and Level rates it Little AI ●○○○; you can [apply on Pfizer](https://jobsbylevel.com/go/b11b3cb0-6144-40e4-ac00-426b3df77365?utm_medium=ai-agent).

AI Level 1, AI centrality 0 out of 100. United States - Washington – Bothell.

## Details

- Company: [Pfizer](https://jobsbylevel.com/companies/pfizer)
- AI level: AI Level 1 (score 0 out of 100)
- Location: United States - Washington – Bothell
- Salary: $94k-$156k
- Posted: November 2, 2026
- Apply: https://jobsbylevel.com/go/b11b3cb0-6144-40e4-ac00-426b3df77365?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=senior-scientist-downstream-process-development-r-d-at-pfizer-685215

## Prepare for this job

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## Description

Job Description ROLE SUMMARY A Senior Scientist (R4) position is available in the Downstream Process Development group within Bioprocess R&D. The successful candidate will have strong laboratory research experience and a desire to remain in a hands‑on, laboratory‑focused role. This position will be part of a multidisciplinary team of scientists across multiple sites focused on the development and optimization of recovery and purification processes for recombinant proteins expressed in mammalian cell culture, supporting early‑ and late‑phase clinical programs. The Senior Scientist will work collaboratively to develop robust, efficient, and scalable downstream strategies to improve process performance and enable successful technology transfer. ROLE RESPONSIBILITIES - Design and execute small‑scale downstream process development studies, with support for pilot‑scale and manufacturing purification activities. - Analyze experimental data to develop, test, and refine hypotheses that improve the fundamental understanding of recovery and purification processes. - Contribute to process characterization, validation strategies, Quality by Design (QbD) approaches, and regulatory filings. - Author internally reviewed technical reports, present scientific results to cross‑functional teams and management, and publish externally as appropriate. - Identify and implement opportunities for operational efficiency and continuous improvement across Bioprocess R&D workflows. - Support change initiatives related to business infrastructure, platforms, and technologies to enable pipeline, legacy, and innovation programs. BASIC QUALIFICATIONS Education Bachelor’s degree with 8+ years of relevant experience, or Master’s degree with 6+ years of relevant experience, or PhD with 0–3 years of experience Degrees should be in a biological or engineering discipline (e.g., Biotechnology, Chemistry/Biochemistry, Chemical or Biochemical Engineering, or equivalent). Experience/Skills Hands‑on experience in recombinant protein downstream process development, technology transfer, and/or bioprocess manufacturing. Strong understanding of protein chemistry and protein analytics, with demonstrated ability to apply current scientific literature. Proven ability to independently drive experimental work, deliver results, and contribute innovative solutions within project teams. Highly organized, self‑motivated, and capable of working both independently and collaboratively in a matrix environment. Excellent written and verbal communication skills, including technical documentation and presentations. Strong analytical, data interpretation, and computer skills. Ability to manage personal workload effectively and contribute to planning of people and technology resources within project teams. Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity. Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use. PREFERRED QUALIFICATIONS Experience with recovery and purification of recombinant proteins from mammalian and microbial or yeast expression systems. Experience transferring biologics processes to pilot‑scale or commercial manufacturing, including familiarity with data acquisition and process control systems. Experience supporting late‑stage development, process validation, and commercialization activities. Working knowledge of statistical experimental design and data analysis. Broad understanding of the biologics drug development process and requirements for advancing candidates through clinical development. Work Location Assignment: On Premise The annual base salary for this position ranges from $93,600.00 to $156,000.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 12.5% of the base salary and

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