# Sr Director, Clinical Excellence Group Lead (I&I) at Pfizer

AI Level 1, AI centrality 30 out of 100. United States - Massachusetts - Cambridge.

## Details

- Company: [Pfizer](https://jobsbylevel.com/companies/pfizer)
- AI level: AI Level 1 (score 30 out of 100)
- Location: United States - Massachusetts - Cambridge
- Salary: $215k-$358k
- Posted: October 6, 2026
- Apply: https://jobsbylevel.com/go/abee5747-b952-47fc-81f6-dbd245c0bee0

## Description

The Inflammation & Immunology Clinical Excellence & Innovation organization is seeking an experienced and enterprise-minded clinical development leader to serve as Senior Director, Clinical Excellence Group Lead. This highly visible role provides strategic clinical, scientific, operational, and people leadership across a portfolio of complex clinical development programs. The successful candidate will lead and develop a team of clinical scientists while ensuring oversight of clinical integrity, scientific quality, patient safety, and disciplined execution across studies within the Dermatology Franchise. This leader will also help advance new ways of working, including the responsible integration of AI-enabled, digital, data, and advanced analytics capabilities to improve clinical development quality, speed, and decision-making. As a senior change leader within a highly experienced matrix organization, this individual will bring strategic clarity, operational discipline, and collaborative influence to address portfolio challenges, optimize resource allocation, and scale effective solutions across the clinical trial lifecycle. KEY RESPONSIBILITIES Team Leadership & Change Management Lead, mentor, and develop a team of high-performing clinical scientists, fostering a culture of collaboration, accountability, continuous learning, intellectual curiosity, and agility. Act as a change champion, guiding a highly tenured organization through digital transformation and new ways of working. Drive change management initiatives that encourage the adoption of innovative tools and process optimizations without compromising scientific rigor. Build strong, collaborative partnerships with Clinical Operations, Data Science, Biostatistics, Digital/Technology, Regulatory, Medical Affairs, Portfolio Strategy, and Business Operations to align clinical science objectives with broader enterprise goals. Portfolio planning, lifecycle management, and evaluation of future growth opportunities. Business Operations & Enterprise Strategy · Apply strong business acumen to identify operational bottlenecks within clinical development and lead cross-functional workstreams to design and implement scalable solutions. Partner with cross-functional teams on enterprise initiatives to develop and implement fit-for-purpose operating practices, tools, and governance approaches that enable a well-controlled, flexible organization with strong fiscal management, cross-team communication, and efficient workflows. Establish and leverage standardized frameworks to evaluate clinical program designs, resource needs, and workflows through an operational efficiency lens, ensuring resources are optimized and key milestones are supported. Support generating business insights, metrics, and dashboards to inform decision-making, monitor therapeutic area performance, and identify opportunities to improve quality, speed, productivity, and portfolio impact. Navigate a complex matrix environment with an enterprise mindset, ensuring that innovation strategies in I&I can scale and align with broader Pfizer corporate objectives. AI-Enabled Clinical Development & Innovation · Partner closely with data science, digital, and technology teams to translate complex AI use cases into practical, scalable, compliant workflows for study teams. · Lead the identification, strategic development, and implementation of AI/ML and advanced analytics tools to optimize clinical trial design and execution. · Direct applied AI/ML approaches across the continuum, including: · Protocol design and optimization · Site selection and feasibility assessment · Patient recruitment and enrollment strategies · Query management and workflow automation · Data cleaning, anomaly detection, and signal identification · Safety risk prediction and proactive mitigation . `Incorporate AI-derived insights and data-driven approaches into overarching clinical strategy and regulatory deliverables. Core Clinical Leadership · Oversee the

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Source: https://jobsbylevel.com/jobs/sr-director-clinical-excellence-group-lead-i-i-at-pfizer-48ed73

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