# Staff Software Engineer at Natera

Natera is hiring a Staff Software Engineer for a remote role open to applicants in United States. Level rates it Little AI ●○○○; you can [apply on Natera](https://jobsbylevel.com/go/378e8e14-8e60-4caf-ab52-a7c66738252d?utm_medium=ai-agent).

AI Level 1, AI centrality 35 out of 100. Remote (US Remote).

## Details

- Company: [Natera](https://jobsbylevel.com/companies/natera)
- AI level: AI Level 1 (score 35 out of 100)
- Location: Remote (US Remote)
- Posted: November 4, 2026
- Apply: https://jobsbylevel.com/go/378e8e14-8e60-4caf-ab52-a7c66738252d?utm_medium=ai-agent
- Free CV review for this job: https://jobsbylevel.com/cv-review?job=staff-software-engineer-at-natera-9f5ca3

## Description

As a Staff Software Engineer , you will lead the design, development, and maintenance of the LIMS application and related software. You will be one of the primary technical leads of the Software Engineering group, working to provide design solutions and general team leadership to other engineers and Technical Product Managers. PRIMARY RESPONSIBILITIES: Work closely with stakeholders and users to define requirements Translate requirements into reliable and extensible operations-friendly applications in Python Work with an engineering team to make key design and technical implementation decisions Have a holistic view of processes and systems involved in taking patient samples from order to result in a multi-product clinical laboratory Understand LIMS platform features and propose solutions that present trade-off analysis and make best use of the platform Leverage off-the-shelf or existing functionality whenever possible so development resources can be focused on unmet needs Integrate other enterprise systems and services to create seamless business processes. Improve development process and procedure and evangelize best practices Develop and maintain automated tests Provide second-tier production support QUALIFICATIONS: BS degree in computer science, comparable program, or equivalent. 10+ years of overall software development experience, preferably building complex data or process management applications in production 10 + years of experience with Python 10+ years of experience with web services (REST, etc) and relational databases Experience with front-end web programming, preferably with modern JavaScript frameworks (react, angular, etc.) Experience in regulated environments (CLIA/CAP, HIPAA, 21 CFR Part 11, ISO 13485, IEC 62304, GxP) and software validation practices Strong relational database skills including database design, migrations, and optimization (PostgreSQL or MySQL preferred) Demonstrated experience leading the replacement or consolidation of legacy or disparate systems into a unified platform NICE TO HAVE: Experience building and configuring LIMS or other laboratory workflow software, and implementing external applications and integrations with a LIMS systems, ideally in a clinical, genomics, or high-throughput setting Experience integrating laboratory instruments and automation KNOWLEDGE, SKILLS, AND ABILITIES: Python (FastAPI, Pydantic, SQLAlchemy or similar ORM) JavaScript / TypeScript Relational Database and SQL Programming, prefer PostgreSQL or MySQL REST APIs and Event-Driven Microservice Architecture Messaging and event streaming (SQS/SNS, Pub/Sub, Kafka) Infrastructure-as-code (Terraform, etc.) Docker or container-oriented technologies The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations. Remote USA $152,100 — $190,100 USD OUR OPPORTUNITY Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability

The description is cut here. Read the full offer: https://jobsbylevel.com/jobs/staff-software-engineer-at-natera-9f5ca3

Source: https://jobsbylevel.com/jobs/staff-software-engineer-at-natera-9f5ca3

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