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Isomorphic Labs

Technical Program Manager (DDMR), Cambridge, MA

Isomorphic Labs is hiring a Technical Program Manager (DDMR), Cambridge, MA (United States). Level rates it ; you can apply on Level.

AI in this role

Technical Program Manager supporting AI-first drug design programs at Isomorphic Labs, facilitating cross-functional coordination between teams.

alphafold
program-managementdrug-discoverycross-functional-leadership

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.

The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery. 

Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.

The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you. 

 

About Iso

Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.

Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.

We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.

Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.

 

Your impact 

As part of the ongoing expansion of our Drug Design and Medical Research (DDMR) function, we are looking to recruit our first Technical Program Manager to our Cambridge, MA office. 

As a member of the Technical Program Management team you will be responsible for facilitating all aspects of small molecule drug discovery program management for Cambridge programs, providing hands-on support to our AI-first Drug Design programs, ensuring smooth integration with our London office. You will work in alignment with the drug design teams in Cambridge and liaise with key internal stakeholders across finance, legal, alliance management and AI/tech.

If you are an organised, skilled and ambitious individual looking to take the next step in your career, joining Isomorphic Labs now will lift you out of your comfort zone and provide you with an amazing opportunity for personal growth and development. 

 

What you will do 

  • As a member of the TPM team you will be responsible for supporting DDMR with program planning, dynamically monitoring timelines, action tracking, risk reporting, driving effective meetings and stakeholder management
  • You will manage and monitor program budgets with respect to forecasting and actual spend to support the program team, DDMR and TPM team as well as report out to senior stakeholders
  • You will provide help to program teams to effectively liaise with CROs and other external providers/partners, helping with contract reviews and processing
  • You will help to build and embed processes and operating systems, ensuring integration and alignment across Isolabs

 

Skills and qualifications 

Essential:
  • At least a BSc in Biology, Chemistry or related discipline
  • Proven industry experience in contributing to, managing or leading early stage / discovery small molecule and / or glue and / or peptide drug design programs 
  • Understanding of small molecule / glue / peptide drug discovery & development processes in the context of project & program planning, and governance 
  • Experience of managing budgets, including planning, forecasting, monitoring, troubleshooting and working to identify efficiencies
  • Experience of operational program management processes
  • Experience with program risk management
  • Experience supporting teams in fast-paced and constantly changing environments 
  • Ability to adaptively interact and confidently communicate with diverse key stakeholders
  • Patient, organised and detail-oriented

Nice to have:

  • Advanced degree in Biology, Chemistry or related discipline
  • Program management qualification
  • Experience of working in an ML drug discovery environment
  • Working with Jira and / or confluence or other program management software

 


Culture and values

We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it. 

Thoughtful
Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.

Brave
Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.

Determined
Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.

Together
Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.


Creating an extraordinary company

We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.

We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.


Hybrid working

It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.

Please note that when you submit an application, your data will be processed in line with our privacy policy.


>> Click to view other open roles at Isomorphic Labs

How we rate this

Technical Program Manager (DDMR), Cambridge, MA at Isomorphic Labs rates 65 out of 100 for how much of the daily work is AI. That makes it Works on AI (AI Level 3 of 4). The level is about AI in the job, not seniority.

Classification

Works on AI. The daily work is on AI products, without building the model.

  1. ●●●● Builds AI80 to 100
  2. ●●●○ Works on AI60 to 79
  3. ●●○○ Uses AI40 to 59
  4. ●○○○ Little AI0 to 39

Levels come from how often the tools, models and workflows of the role are named in the posting itself. Open the description and count.

Prepare for this job

Built from this posting and from similar jobs on Level.

Skills and AI tools this role asks for

Program ManagementDrug DiscoveryCross Functional LeadershipAlphafold

Questions you could be asked

  1. Tell me about a project where program management was part of your work. What did you do?
  2. Tell me about a project where drug discovery was part of your work. What did you do?
  3. Tell me about a project where cross functional leadership was part of your work. What did you do?
  4. What's a project where you used Alphafold hands-on?
  5. Describe a typical day in a role like this one: which parts run through AI directly?

Adapt your resume

  • List these exact terms on your resume: Program Management, Drug Discovery, Cross Functional Leadership, and Alphafold. An applicant tracking system matches the wording, not the idea.
  • Attach one line of real, concrete experience to at least one of them. A tool named with nothing behind it rarely survives a human read.
  • Show where AI is part of your daily process, not a one-off project. This role expects it to be a running habit.

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