Proteomics Summer Intern 2027

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Job Description:

The Summer Graduate Intern, Translational Systems Toxicology, will join the multidisciplinary Translational Safety team within Preclinical Sciences and Translational Safety (PSTS) and gain hands-on experience supporting proteomics-based translational research. The intern will contribute to the development, optimization, and evaluation of sample preparation workflows for mass spectrometry-based proteomics, with a focus on improving robustness, throughput, scalability, and automation readiness across a variety of biological sample types, including blood- and tissue-derived samples.

Key Responsibilities

• Supporting the development, optimization, and evaluation of proteomics sample preparation workflows for biological samples, including blood- and tissue-derived matrices
• Assessing and comparing sample preparation approaches to improve analytical performance, reproducibility, throughput, and suitability for downstream mass spectrometry analysis
• Exploring strategies to enable robust proteomic analysis from challenging or limited-volume samples, when appropriate
• Developing and adapting sample preparation workflows for laboratory automation platforms such as the Agilent AssayMAP Bravo
• Collaborating with cross-functional scientists to design experiments, analyze results, and interpret findings
• Performing protein extraction, digestion, peptide cleanup, and other proteomics sample preparation procedures using established laboratory practices
• Analyzing experimental data and summarizing results using appropriate software and computational tools
• Maintain clear experimental records, troubleshoot technical challenges, and communicate progress, results, and recommendations to cross-functional collaborators
• Summarize the project in a final presentation/poster and provide a concise, reproducible workflow and recommendations for future development

Required Qualifications

• Availability to participate in a Summer 2027 internship program, with expected dates ranging from May-August 2027 or mid-June to mid-September 2027.
• Currently pursuing a Master's or PhD degree in Biochemistry, Analytical Chemistry, Proteomics, or a related scientific field and enrolled at an accredited university during the internship period
• Candidates must have completed at least one year of graduate study by Summer 2027.
• Students entering their second or third year of a Master's or PhD program are encouraged to apply
• Hands-on laboratory experience with biological samples and fundamental techniques such as accurate pipetting, buffer preparation, centrifugation, and sample handling
• Ability to plan and execute experiments with appropriate guidance, maintain organized records, and work safely in a laboratory environment
• Strong analytical, problem-solving, verbal communication, written communication, and collaboration skills
• Scientific curiosity, self-motivation, and the ability to work both independently and as part of a multidisciplinary team
  
  

Preferred Qualifications

• Prior experience with proteomics or mass spectrometry sample preparation, particularly low-input, blood-derived, or cell-based samples
• Familiarity with common proteomic sample-preparation methods, including in-solution digestion, S-Trap, SP3, or peptide cleanup workflows
• Experience with liquid-handling automation or the Agilent AssayMAP Bravo platform
• Exposure to LC-MS/MS instrumentation, including Bruker timsTOF systems, and proteomics data-analysis software such as Spectronaut
• Working knowledge of R, Python, or another language used for scientific data analysis
• Experience handling blood, PBMCs, or samples from humans and preclinical species is beneficial

Candidate Eligibility Requirements

Candidates must:

• Be authorized to work in the US without current or future sponsorship requirements.
• Remain actively enrolled in their academic program throughout the entire internship period.
• Be available to work 40 hours per week during the internship.
• Should have a minimum GPA of 3

Permanently authorized to work in the U.S., must not require sponsorship of an employment visa (e.g., H-1B or green card) at the time of application or in the future.  Students currently on CPT, OPT, or STEM OPT usually requires future sponsorship for long term employment and do not meet the requirements for this program unless eligible for an alternative long-term status that does not require company sponsorship.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. 

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation,  external applicants please contact us via https://www.jnj.com/contact-us/careers . Internal employees contact AskGS to be directed to your accommodation resource.

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