SDE II, Life Sciences Applied AI

Amazon is hiring an SDE II, Life Sciences Applied AI in Seattle, United States. It pays $144k-$194k a year and Level rates it ; you can apply on Amazon.

Level's read on this job

Level rates this software engineer role Builds AI ●●●●: the job is building AI systems.
The posting mentions AWS, Python and AI agents among its tools and skills.
Level classes it as a mid-level role.
Amazon has 21,000+ other open roles on Level.

AI in this role

Build 0-to-1 enterprise applications orchestrating AI agents to streamline clinical trials in AWS Applied AI.

awspython

ai-agentssoftware-engineeringdistributed-systemscloud-computing

As part of the AWS Applied AI Solutions organization, we have a vision to provide business applications, leveraging Amazon’s unique experience and expertise, that are used by millions of companies worldwide to manage day-to-day operations. We will accomplish this by accelerating our customers’ businesses through delivery of intuitive and differentiated technology solutions that solve enduring business challenges. We blend vision with curiosity and Amazon’s real-world experience to build opinionated, turnkey solutions. Where customers prefer to buy over build, we become their trusted partner with solutions that are no-brainers to buy and easy to use.

AWS Life Sciences in Applied AI Solutions org is working on new AI agent(s) in the clinical trials domain. Clinical trials are the most time consuming and cost heavy step in bringing new drugs to market and we aim to accelerate this process resulting in better health outcomes for patients.

It's a new product in an space that offers massive opportunity for AWS. Come be part of this 0->1 journey. We're building an end-user enterprise application that orchestrates multiple AI agents to streamline the entire clinical trial process, from planning, monitoring to regulatory submission.

We are looking for an SDE with a strong sense of ownership, bias-for-action who can help drive the design and development of complex features, who can partner with Product, Science, UX teams to solve problems, and can be an enthusiastic member on the team.

We are a small start-up team colocated in one-location working on an ambiguous problem that offers a lot of scope and influence beyond the technical realm.

About the team
ABOUT AWS:

Diverse Experiences
Amazon values diverse experiences. Even if you do not meet all of the preferred qualifications and skills listed in the job description, we encourage candidates to apply. If your career is just starting, hasn’t followed a traditional path, or includes alternative experiences, don’t let it stop you from applying.

Why AWS
Amazon Web Services (AWS) is the world’s most comprehensive and broadly adopted cloud platform. We pioneered cloud computing and never stopped innovating — that’s why customers from the most successful startups to Global 500 companies trust our robust suite of products and services to power their businesses.

Work/Life Balance
We value work-life harmony. Achieving success at work should never come at the expense of sacrifices at home, which is why flexible work hours and arrangements are part of our culture. When we feel supported in the workplace and at home, there’s nothing we can’t achieve in the cloud.

Inclusive Team Culture
Here at AWS, it’s in our nature to learn and be curious. Our employee-led affinity groups foster a culture of inclusion that empower us to be proud of our differences. Ongoing events and learning experiences, including our Conversations on Race and Ethnicity and AmazeCon conferences, inspire us to never stop embracing our uniqueness.

Mentorship and Career Growth
We’re continuously raising our performance bar as we strive to become Earth’s Best Employer. That’s why you’ll find endless knowledge-sharing, mentorship and other career-advancing resources here to help you develop into a better-rounded professional.

Basic qualifications

- 3+ years of non-internship professional software development experience
- 2+ years of non-internship design or architecture (design patterns, reliability and scaling) of new and existing systems experience
- Experience programming with at least one software programming language

Preferred qualifications

- 3+ years of full software development life cycle, including coding standards, code reviews, source control management, build processes, testing, and operations experience
- Bachelor's degree in computer science or equivalent

Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.

Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit https://amazon.jobs/content/en/how-we-hire/accommodations for more information. If the country/region you’re applying in isn’t listed, please contact your Recruiting Partner.

The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at https://amazon.jobs/en/benefits.

USA, WA, Seattle - 143,700.00 - 194,400.00 USD annually

How we rate this

SDE II, Life Sciences Applied AI at Amazon rates 85 out of 100 for how much of the daily work is AI. That makes it Builds AI (AI Level 4 of 4). The level is about AI in the job, not seniority.

Classification

Builds AI. The job is building AI systems.

●●●● Builds AI80 to 100
●●●○ Works on AI60 to 79
●●○○ Uses AI40 to 59
●○○○ Little AI0 to 39

Levels come from how often the tools, models and workflows of the role are named in the posting itself. Read the description and count the AI tools, models and workflows it names.

Key facts

SDE II, Life Sciences Applied AI is an open job at Amazon.
Level rates this role AI Level 4 of 4: Builds AI.
The listed salary is $144k-$194k a year.
The role is based in US, WA, Seattle.
The job was posted on October 5, 2026.
Seniority: mid.
Applications are handled by Amazon. Apply on Amazon

Prepare for this job

Built from this posting and from similar jobs on Level.

Skills and AI tools this role asks for

AI agentsSoftware EngineeringDistributed SystemsCloud ComputingAWSPython

Also common in software engineer jobs at this level

Python LLM C++Machine learning Kubernetes Java

Pay

This job starts at: $144k
Typical software engineer job: $167k

This posting starts 14% below the typical software engineer job. See software engineer jobs

Questions you could be asked

How do you decide when an AI agent can act on its own versus asking for approval first?
Tell me about a project where software engineering was part of your work. What did you do?
Tell me about a project where distributed systems was part of your work. What did you do?
Tell me about a project where cloud computing was part of your work. What did you do?
Walk me through how you've used AWS in your day-to-day work.

Adapt your resume

List these exact terms on your resume: AI agents, Software Engineering, Distributed Systems, Cloud Computing, and AWS. An applicant tracking system matches the wording, not the idea.
Attach one line of real, concrete experience to at least one of them. A tool named with nothing behind it rarely survives a human read.
Lead with what you built, trained or shipped. This role is judged on the AI system itself, not the tools around it.

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