(Senior) Director, Clinical Pharmacology

AstraZeneca is hiring a (Senior) Director, Clinical Pharmacology. Level rates it ; you can apply on AstraZeneca.

Level's read on this job

On Level's scale, this role is Little AI ●○○○: aI is not part of the work.
The posting mentions clinical pharmacology, pharmacometrics and toxicology among its tools and skills.
Level classes it as a senior role.
AstraZeneca has 1,200+ other open roles on Level.

AI in this role

Leads the clinical pharmacology group, providing expert guidance in drug development programs and exploring process improvements including AI/ML.

clinical-pharmacologypharmacometricstoxicologypharmacokineticsleadership

Summary

Lead the clinical pharmacology (CP) group of ~10 members, including clinical pharmacologists, pharmacometricians and toxicologists, to support global and/or regional development projects, ensuring all deliverables are based on science with high quality and timeliness.

Responsibilities

Provide CP expertise and guidance in clinical drug development programs of all therapeutic areas in study design (including dose rationales), data analyses to learn dose-exposure-response relationships and their variabilities, result interpretations and reporting
Supervise and work with pharmacometricians in conducting PK (and/or PD) analysis (e.g., to integrate all regional data and investigate ethnic differences) for regulatory submissions in China
Engage with management, regional and global (internal and external) stakeholders to drive CP strategies at project and portfolio levels
Establish best practices for CP processes activities (e.g., modeling and simulation) to seek efficiency. Implement and explore process and data analysis strategies including AI/ML for science/innovation and for productivity
Guide CP members in career development; coach and train junior members in applying quantitative methods and PK-PD knowledge to clinical projects

Qualifications

Ph.D./PharmD/MD in relevant disciplines (CP, pharmacokinetics [PK], , toxicokinetics, pharmacometrics) or other equivalent degrees or knowledge/expertise
8+ years of relevant clinical development experience in CP or Modeling & Simulation (M&S) roles
Adequate people management experience with proven track records as a coach/trainer
Excellent communication and negotiating skills with fluent in English (oral and written)
Decent scientific publication records

Skills

In-depth understanding of CP, pharmacometrics, and their interfaces with (and good understanding of) DMPK, toxicology, biostatistics, clinical development, and regulatory science with quantitative, logical approach to drug development and common sensical business acumen.
Ability to translate complex quantitative analyses into clear, actionable insights for cross‑functional and senior stakeholders.
Strong scientific judgment, critical thinking, and decision‑making in ambiguous or data‑limited settings.
Experience of working in global, matrix organizations with high scientific and regulatory standards. Effective management of stakeholders

Date Posted

29-9月-2026

Closing Date

30-12月-2026

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

How we rate this

(Senior) Director, Clinical Pharmacology at AstraZeneca rates 20 out of 100 for how much of the daily work is AI. That makes it Little AI (AI Level 1 of 4). The level is about AI in the job, not seniority.

Classification

Little AI. AI is not part of the work.

●●●● Builds AI80 to 100
●●●○ Works on AI60 to 79
●●○○ Uses AI40 to 59
●○○○ Little AI0 to 39

Levels come from how often the tools, models and workflows of the role are named in the posting itself. Read the description and count the AI tools, models and workflows it names.

Key facts

(Senior) Director, Clinical Pharmacology is an open job at AstraZeneca.
Level rates this role AI Level 1 of 4: Little AI.
The role is based in Shanghai Jing'An Office.
The job was posted on September 29, 2026.
Seniority: senior.
Applications are handled by AstraZeneca. Apply on AstraZeneca

Prepare for this job

Built from this posting and from similar jobs on Level.

Skills and AI tools this role asks for

Clinical PharmacologyPharmacometricsToxicologyPharmacokineticsLeadership

Questions you could be asked

Tell me about a project where clinical pharmacology was part of your work. What did you do?
Tell me about a project where pharmacometrics was part of your work. What did you do?
Tell me about a project where toxicology was part of your work. What did you do?
Tell me about a project where pharmacokinetics was part of your work. What did you do?
Tell me about a project where leadership was part of your work. What did you do?

Adapt your resume

List these exact terms on your resume: Clinical Pharmacology, Pharmacometrics, Toxicology, Pharmacokinetics, and Leadership. An applicant tracking system matches the wording, not the idea.
Attach one line of real, concrete experience to at least one of them. A tool named with nothing behind it rarely survives a human read.

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