Senior/Principal Clinical Pharmacologist
AstraZeneca is hiring a Senior/Principal Clinical Pharmacologist. Level rates it ; you can apply on AstraZeneca.
Level's read on this job
- Level rates this role Little AI ●○○○: aI is not part of the work.
- The posting mentions Modeling And Simulation, pharmacokinetics and pharmacodynamics among its tools and skills.
- Level classes it as a senior role.
- AstraZeneca has 1,400+ other open roles on Level.
AI in this role
Lead clinical pharmacologist to drive PK/PD modelling and simulation approaches in drug development programs.
Typical Accountabilities
· Ensure the optimal application of clinical pharmacokinetics (PK), pharmacodynamics (PD), and modelling & simulation (M&S) in clinical development programs, including:
1. Design and conduct clinical studies including CP studies (dosing rationales, sampling schemes, etc.)
2. Data analyses (e.g., M&S) to elucidate dose-exposure-response relationships, and result interpretations
3. Play a central role in justifying dose recommendations for Asian population by using quantitative approaches
4. Promote M&S approaches in clinical development programs whenever applicable
5. When applicable, develop mathematical and statistical models to understand disease mechanism, its progression, and PK/PD; conduct meta-analyses as appropriate to maximize data use.
6. Preparation and defence of regulatory submissions, as well as regulatory interactions such as end of phase consultation meetings, query response, etc.
· Interact with internal and external stakeholders for assigned projects
· Literature research and knowledge sharing; publish clinical pharmacology-related research articles and reviews in peer-reviewed journals, when applicable
· Train junior CP staff
Education, Qualifications, Skills and Experience
Essential
- Advanced training with a degree such as PhD, PharmD, and MD to enable a successful career in the field. Applicant with a master’s degree should have a strong technical background and have been successfully delivering the drug development projects before.
- Experienced in drug clinical development
- Proficiency in oral and written mandarin and English;
- Capability to provide own learnings, ideas, and experiences to internal stakeholders
- Excellent communication, analytical and problem-solving skills
- Experience with both early and late phase clinical development
Date Posted
06-8月-2026Closing Date
30-12月-2026AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
How we rate this
Senior/Principal Clinical Pharmacologist at AstraZeneca rates 10 out of 100 for how much of the daily work is AI. That makes it Little AI (AI Level 1 of 4). The level is about AI in the job, not seniority.
Little AI. AI is not part of the work.
- ●●●● Builds AI80 to 100
- ●●●○ Works on AI60 to 79
- ●●○○ Uses AI40 to 59
- ●○○○ Little AI0 to 39
Levels come from how often the tools, models and workflows of the role are named in the posting itself. Read the description and count the AI tools, models and workflows it names.
Prepare for this job
Built from this posting and from similar jobs on Level.
Skills and AI tools this role asks for
Questions you could be asked
- Tell me about a project where pharmacokinetics was part of your work. What did you do?
- Tell me about a project where pharmacodynamics was part of your work. What did you do?
- Tell me about a project where clinical development was part of your work. What did you do?
- Tell me about a project where data analysis was part of your work. What did you do?
- Walk me through how you've used Modeling And Simulation in your day-to-day work.
Adapt your resume
- List these exact terms on your resume: Pharmacokinetics, Pharmacodynamics, Clinical Development, Data Analysis, and Modeling And Simulation. An applicant tracking system matches the wording, not the idea.
- Attach one line of real, concrete experience to at least one of them. A tool named with nothing behind it rarely survives a human read.
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