Senior Principal - Portfolio Manager

About the Team:

Enterprise Systems is the backbone of GSK’s internal operations in Digital & Tech, enabling GSK Global Functions teams such as Finance, Procurement, HR, Legal, Compliance, WREF, CGA and Corporate Secretariat to run seamlessly. This team designs and delivers cutting-edge digital platforms that power critical processes, ensuring efficiency, compliance, and scalability across the enterprise.

Enterprise Systems Management & Business Operations delivers digital solutions that support Enterprise Systems running as a high-performing organization. This team drives financial discipline, operational rigor and strategic alignment across the ES portfolio that safeguard GSK’s integrity and reputation globally. By joining this team, you’ll help shape systems that support thousands of employees worldwide, driving innovation and reliability in the tools that keep GSK moving forward.

Job Purpose:

GSK’s Global Supply Chain D&T team is the front facing business tech group supporting GSK’s critical business of Global Manufacturing across all product portfolios. The team comprises of multiple business tech disciplines from site specific D&T partnering through to above site and global services like Data & Analytics and Global Demand & Supply Planning processes.

The Team consists of a set of portfolio and business operations manager aligned to GSC D&T Towers and VPs. The team is responsible for defining as well as ensuring portfolio delivery processes, standards, reporting and governance,are adhered to and understood by product owners and VPs across GSC D&T. The team is also responsible for PMO delivery toolset and its maintenance.

In addition the team is accountable for business operations for each of the towers, in ensuring all Finance, HC and Contracts are clearly understood and driven with the respective GSC D&T LT members, VPs.

Key Responsibilities

• Lead the Portfolio Management service for an assigned GSC D&T Tower, partnering with Tower LT and Product Directors to optimise value delivery across projects and epics.
• Define, maintain and embed portfolio delivery framework, standards, reporting and governance in line with GSCD&T product/portfolio model and PMO guidance.
• Ensure portfolio data quality (scope, status, RAG, milestones, risks, dependencies) and financial information are accurate and ready for governance forums and Portfolio Reviews.
• Prepare and lead Tower portfolio review sessions, highlighting key red/amber items, tracking actions to “back to amber/green” and feeding into GSCD&T Portfolio Review.
• Support prioritization and discretionary budget allocation decisions across the Tower using data-driven insights on Capex/Opex, benefits, risks and impacts. Ensure every initiative has a baseline, a named benefit owner and a measurement schedule, track benefits beyond closure, and feed actuals back into prioritization.
• Work closely with Finance and the Senior Business Operations Manager to ensure finance, headcount and contract/vendor information is clearly understood, controlled and reflected in portfolio reporting.
• Champion GSCD&T portfolio standards and tools (Aha! workspaces, ADO/Jira integration, Power BI dashboards) and support teams to adopt. Coach Product Owners and Tower teams on portfolio discipline so that transparency improves at source.
• Provide support to projects on managing risks, cross-stream dependencies and impediments, escalating through Tower LT and GSCD&T governance where needed. Hold the integrated Tower plan (sequencing, dependencies, capacity and RAID), challenge delivery on pace and evidence, and escalate before impact through Tower LT and GSCD&T governance.
• Partner during planning sessions/BRPs to assess value, dependencies and capacity across the portfolio and ensure alignment with integrated roadmaps and key programmes (e.g. ERP, Smart Manufacturing, D&AI work).
• Continuously improve portfolio management maturity, standards and insight generation, including leveraging AI/automation use cases.
• Lead your team in using approved AI tools to improve productivity and ways of working, role-modelling responsible use and follow GSK’s Responsible AI, privacy and security requirements.

Basic Qualifications:

• Master’s degree or PhD in Business, Supply Chain/Operations, Technology, Information Systems, Computer Science, or a related discipline.
• 10+ years of experience in supply chain, manufacturing, quality, digital/technology, or a related business environment.
• Experience leading technology-enabled portfolios and/or programmes.
• Experience delivering digital or technology transformation initiatives.
• Experience managing multiple technical projects, products, programmes, or initiatives as part of a portfolio.
• Experience establishing or managing portfolio governance, status reporting, milestones, risks, dependencies, prioritization, and delivery tracking.
• Experience managing operational and/or change budgets valued in the millions of pounds or equivalent currency, including financial tracking and reporting.
• Experience working with senior leadership stakeholders on portfolio priorities, investment decisions, risks, dependencies, and delivery status.
• Experience managing delivery against defined scope, budget, timelines, and quality requirements.
• Experience working with Finance and business/technology teams on portfolio planning, budgeting, or investment management.
• Experience managing risks, cross-programme dependencies, issues, and escalation through governance forums.
• Experience preparing and presenting portfolio performance, financial information, risks, and recommendations to senior stakeholders.
• Experience working across multiple business, technology, finance, and/or geographically distributed teams.
• Availability for business travel as required.

Preferred Qualifications

• Recognized Portfolio Management certification
• Agile / SAFe certification, such as Leading SAFe or SAFe POPM
• Project Management certification, such as PMP or PRINCE2

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Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Inclusion at GSK:

As an employer committed to Inclusion, we encourage you to reach out if you need any adjustments during the recruitment process.

Please contact our Recruitment Team at IN.recruitment-adjustments@gsk.com to discuss your needs.

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