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AstraZeneca

Senior Scientist (Chemistry)

AstraZeneca is hiring a Senior Scientist (Chemistry). Level rates it ; you can apply on AstraZeneca.

Level's read on this job

  • On Level's scale, this role is Little AI ●○○○: aI is not part of the work.
  • The posting mentions In Silico Modelling, Statistics and organic chemistry among its tools and skills.
  • Level classes it as a senior role.
  • AstraZeneca has 1,300+ other open roles on Level.
  • Posted in the last few days.

AI in this role

Supports technical contribution, process optimization, and chemistry operations for commercial pharmaceutical products through lab experimentation.

In Silico ModellingStatistics
organic-chemistryprocess-optimizationtech-transferregulatory-submissionsproblem-solving

Senior Scientist (Chemistry)

Location: Dublin

Competitive Salary and Benefits


Accountabilities:
As a Senior Scientist, you will be responsible for supporting the technical contribution to transfer, maintain and optimise supply for one or more AstraZeneca commercial products. You will identify, develop and implement process improvements for both launch and commercial products through the use of existing and cutting-edge technologies. You will also provide expert technical input through laboratory experimentation, in-silico modelling and direct manufacturing support at our internal AZ API manufacturing site in Dublin. Your role will also involve contribution to the CMC components of regulatory submissions and preparation of successful query responses over the commercial life of a product.


Essential Skills/Experience:
- BSc/PhD level education in a relevant discipline and experience working within a Research & Development or Manufacturing environment, within the pharmaceutical industry.
- Technical expertise and understanding of practical synthetic organic chemistry spanning across both lab and manufacture.

- Experience in the Tech Transfer of pharmaceutical small molecule Drug Substance processes

- Background in dealing with the challenges of both the scale up and scale down of processes
- A good understanding of the overall drug development process from discovery through to launch.
- A thorough understanding of the principles and management of SHE and cGMP.

- Excellent communication and strategic influencing skills across interfaces of discipline, culture, and expertise both internally and externally.

- Proven problem solver with in depth technical skills.

- Proficiency in the use of statistics to understand data.

- Ability to think and operate across functional boundaries, challenge the status quo and seek opportunities for business improvement.



Desirable Skills/Experience:
- Experience of delivering CMC content or contributions to regulatory filings throughout the life cycle of process development, in the pharmaceutical industry.

- Experience working within a Research & Development and Manufacturing environment in the pharmaceutical industry

- Experience of technical supervision and leading small teams of people or scientific projects.

- Experience of late stage development or commercial supply with a background in a process chemistry skill group

- Experience of working across skillsets (e.g. with chemists, analysts and physical properties experts).


Why AstraZeneca?

At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients, and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth, and development!


So, What's Next

If you are already imagining yourself joining our team, Good, because we can’t wait to hear from you!

Find out more on Social Media:


We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Date Posted

09-Nov-2026

Closing Date

21-Nov-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

How we rate this

Senior Scientist (Chemistry) at AstraZeneca rates 0 out of 100 for how much of the daily work is AI. That makes it Little AI (AI Level 1 of 4). The level is about AI in the job, not seniority.

Classification

Little AI. AI is not part of the work.

  1. ●●●● Builds AI80 to 100
  2. ●●●○ Works on AI60 to 79
  3. ●●○○ Uses AI40 to 59
  4. ●○○○ Little AI0 to 39

Levels come from how often the tools, models and workflows of the role are named in the posting itself. Read the description and count the AI tools, models and workflows it names.

Prepare for this job

Built from this posting and from similar jobs on Level.

Skills and AI tools this role asks for

Organic ChemistryProcess OptimizationTech TransferRegulatory SubmissionsProblem SolvingIn Silico ModellingStatistics

Questions you could be asked

  1. Tell me about a project where organic chemistry was part of your work. What did you do?
  2. Tell me about a project where process optimization was part of your work. What did you do?
  3. Tell me about a project where tech transfer was part of your work. What did you do?
  4. Tell me about a project where regulatory submissions was part of your work. What did you do?
  5. Tell me about a project where problem solving was part of your work. What did you do?

Adapt your resume

  • List these exact terms on your resume: Organic Chemistry, Process Optimization, Tech Transfer, Regulatory Submissions, and Problem Solving. An applicant tracking system matches the wording, not the idea.
  • Attach one line of real, concrete experience to at least one of them. A tool named with nothing behind it rarely survives a human read.

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