Threat Detection and Response Engineering Manager
OpenAI is hiring a Threat Detection and Response Engineering Manager in San Francisco, United States. It pays $401k-$510k a year and Level rates it ; you can apply on OpenAI.
Level's read on this job
- Works on AI ●●●○ is how Level rates this cybersecurity role: the daily work is on AI products, without building the model.
- Pay on this posting starts 150% higher than the typical cybersecurity posting on Level.
- The posting mentions AI research among its tools and skills.
- OpenAI has 819 other open roles on Level.
- Posted in the last few days.
AI in this role
About the team
OpenAI’s mission depends on developing and deploying powerful AI responsibly. Security makes that possible by protecting our research, people, products, and users while enabling progress. We defend sensitive research and other intellectual property, customer data, and the infrastructure behind frontier AI—from GPU supercomputing and multicloud environments to datacenters and emerging agent systems. Threat Detection Engineering builds and operates the detections and investigative workflows that turn adversary activity into effective response.
About the role
We’re looking for a hands-on technical leader to guide the engineers who identify and investigate threats to OpenAI and build the capabilities to contain them. You’ll hire and develop engineers, set technical direction, and prioritize risks to OpenAI’s intellectual property, customer data, and critical infrastructure.
Your team will take an agent-first approach across the detection and response lifecycle, using OpenAI’s models to develop detections, triage signals, investigate suspicious activity, and support bounded response and continuous improvement. You’ll turn advances in model capability into dependable defenses, own their effectiveness, and work with security, research, and infrastructure partners to ensure findings lead to effective action. You’ll establish where agents can act independently and where human judgment and approval are essential.
In this role, you will:
Hire, coach, and develop engineers. Set clear expectations, provide regular feedback, grow technical leadership, and build a team that reviews work rigorously and learns from missed detections and noisy signals.
Set a threat-informed roadmap. Prioritize detection work based on how external and internal actors could target the systems where we train and evaluate frontier models, the production services that run inference and power our products worldwide, the datacenter hardware and networks that support both, and the devices, identities, and applications employees rely on. Balance investment in emerging threats with closing known coverage gaps and keeping existing detections effective.
Own detection and investigation as a complete workflow. Embed agent-driven triage and investigation in the detections your team operates. Surface findings when the evidence points to a likely threat that warrants action. When a finding warrants formal incident response, bring the evidence to the Security Incident Response Team (SIRT) and support the investigation SIRT leads.
Build response and containment capabilities tailored to our infrastructure. Work with infrastructure and system owners to develop and test the controls responders need to contain threats in their environments. Define when human approval is required and how to verify that containment worked.
Apply models across the detection engineering lifecycle. Use OpenAI’s models to help develop threat hypotheses, author and test detections, deploy and tune them, and incorporate investigation findings into better coverage. Evaluate the effectiveness of individual agents and the complete workflows they support.
Turn model advances into tested defenses. Prototype new approaches using OpenAI’s models, evaluate them against realistic adversary behavior and analyst baselines, and move successful experiments into production. Use operational evidence to identify model limitations and partner with Research and Engineering to address them.
Anticipate emerging threats. Translate adversary intelligence and incident findings into testable detection hypotheses. Work with researchers and infrastructure owners on risks specific to a frontier AI lab, such as increasingly capable agents operating across systems with access to sensitive research. Determine what evidence would reveal compromise and what response would be effective.
Establish the visibility needed to detect, investigate, and respond. Partner with Security Observability and infrastructure owners to define telemetry and forensic data requirements. Drive improvements where missing evidence, unreliable data, or limited controls prevent the team from identifying threats or taking effective action.
Engineer for measurable security outcomes. Use replay, adversarial validation, and regression testing to assess whether workflows find intended threats, distinguish benign activity, and reach defensible conclusions. Establish code review, documentation, staged rollout, monitoring, and rollback practices. Measure coverage, investigation accuracy, time to identify threats, and effectiveness of response.
Contribute during incidents. The Security Incident Response Team (SIRT) leads formal incident response. Your team contributes investigative expertise and uses incident findings to improve detections.
You might thrive in this role if you:
Think like an adversary and demand evidence as a defender. You question whether apparent coverage would survive a determined attacker, distinguish plausible explanations from supported conclusions, and stay accountable for threats that existing tools and playbooks miss.
Have managed security or software engineers and can demonstrate how you have hired, coached, developed technical judgment, and improved a team’s ability to deliver.
Are a hands-on builder who can prototype tools, write and review code, and guide engineers through complex detection, investigation, and response designs.
Bring strong AI fluency and have built systems that test how models or agents can improve cyber defense. You have evaluated real security workflows against meaningful baselines and can explain what improved, what failed, and what you changed. You understand model failure modes and design reliable workflows with bounded permissions and clear human decision points.
Have built or operated threat detections and led technical investigations. You understand adversary tradecraft and can assess evidence, scope, and uncertainty across complex environments.
Understand how identity, endpoint, cloud, Kubernetes, and infrastructure telemetry supports investigations. You can reason about response and containment in unfamiliar systems and work with their owners to build practical capabilities.
Have used testing and operational feedback to improve security outcomes. You can explain tradeoffs among coverage, accuracy, speed, and human workload, and choose measures that reflect whether threats are being found and addressed.
Can build a focused roadmap and strong cross-functional partnerships in a rapidly changing environment. You enable researchers and engineers to move quickly while following through on security requirements and dependable operations.
About OpenAI
OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely deploy them to the world through our products. AI is an extremely powerful tool that must be created with safety and human needs at its core, and to achieve our mission, we must encompass and value the many different perspectives, voices, and experiences that form the full spectrum of humanity.
We are an equal opportunity employer, and we do not discriminate on the basis of race, religion, color, national origin, sex, sexual orientation, age, veteran status, disability, genetic information, or other applicable legally protected characteristic.
For additional information, please see OpenAI’s Affirmative Action and Equal Employment Opportunity Policy Statement.
Background checks for applicants will be administered in accordance with applicable law, and qualified applicants with arrest or conviction records will be considered for employment consistent with those laws, including the San Francisco Fair Chance Ordinance, the Los Angeles County Fair Chance Ordinance for Employers, and the California Fair Chance Act, for US-based candidates. For unincorporated Los Angeles County workers: we reasonably believe that criminal history may have a direct, adverse and negative relationship with the following job duties, potentially resulting in the withdrawal of a conditional offer of employment: protect computer hardware entrusted to you from theft, loss or damage; return all computer hardware in your possession (including the data contained therein) upon termination of employment or end of assignment; and maintain the confidentiality of proprietary, confidential, and non-public information. In addition, job duties require access to secure and protected information technology systems and related data security obligations.
To notify OpenAI that you believe this job posting is non-compliant, please submit a report through this form. No response will be provided to inquiries unrelated to job posting compliance.
We are committed to providing reasonable accommodations to applicants with disabilities, and requests can be made via this link.
OpenAI Global Applicant Privacy Policy
At OpenAI, we believe artificial intelligence has the potential to help people solve immense global challenges, and we want the upside of AI to be widely shared. Join us in shaping the future of technology.
How we rate this
Threat Detection and Response Engineering Manager at OpenAI rates 63 out of 100 for how much of the daily work is AI. That makes it Works on AI (AI Level 3 of 4). The level is about AI in the job, not seniority.
Works on AI. The daily work is on AI products, without building the model.
- ●●●● Builds AI80 to 100
- ●●●○ Works on AI60 to 79
- ●●○○ Uses AI40 to 59
- ●○○○ Little AI0 to 39
Levels come from how often the tools, models and workflows of the role are named in the posting itself. Read the description and count the AI tools, models and workflows it names.
Prepare for this job
Built from this posting and from similar jobs on Level.
Skills and AI tools this role asks for
Pay
- This job starts at
- $401k
- Typical cybersecurity job
- $161k
This posting starts 150% above the typical cybersecurity job. See cybersecurity jobs
Questions you could be asked
- Tell me about a research question you investigated. What did you find?
- Describe a typical day in a role like this one: which parts run through AI directly?
- If you removed AI from this role, what would be left, and how do you decide what still needs a human?
Adapt your resume
- List these exact terms on your resume: AI Research. An applicant tracking system matches the wording, not the idea.
- Attach one line of real, concrete experience to at least one of them. A tool named with nothing behind it rarely survives a human read.
- Show where AI is part of your daily process, not a one-off project. This role expects it to be a running habit.
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