Level

LatchBio

AI Biologist - Metagenomics

AI in this role

ai-agents

Ai Biologist - Metagenomics

As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high-performance agents for biological data analysis, empowering over 5,000 scientists across 150+ R&D labs to handle data from instrument-to-insights.

We're seeking a Ai Biologist to join our Metagenomics team, working at the frontier of what artificial intelligence can achieve in biology.

About the Role

You will contribute to our technical approach for evaluating how AI agents reason through complex microbiome and metagenomics datasets. Working with software engineers and computational biologists, you'll build ground-truth benchmark datasets: drawn from real published microbiome studies, that rigorously test whether agents can perform the critical analytical and interpretive steps that expert microbiome researchers execute.

Your deep expertise in microbiome biology, metagenomics analysis, and the ability to identify confounders and technical artifacts will define how we measure agent capability in computational microbiology.

Requirements

  • Master's or PhD in microbiology, microbial ecology, bioinformatics, biology, or related field

  • 3+ years of hands-on research experience with microbiome or metagenomics data, demonstrated through publications or industry work

  • Deep expertise in at least one of:

    • Human microbiome and disease (e.g. IBD, CRC, obesity)

    • Longitudinal microbiome or microbiome interventions (e.g. FMT, diet, antibiotics)

    • Microbial function and metabolism

    • Plant, soil, or environmental microbial ecology

  • Experience interpreting microbiome data in biological context and identifying confounders, technical artifacts, and limitations of the underlying experiments

  • Proficiency in Python and/or R for biological data analysis and visualization

  • Familiarity with 16S and/or shotgun metagenomics, including taxonomic, functional, and community-level analysis



Nice-to-Have

  • Hands-on experience designing or troubleshooting microbiome experiments, including sampling, extraction, controls, or library preparation

  • Experience integrating metagenomics with metabolomics, metatranscriptomics, host omics, or clinical phenotypes

  • Experience with strain-level analysis, metagenomic assembly, MAGs, or long-read sequencing

Culture @ Latch

How we work. Genuinely flexible schedules - we just ask that you communicate when you're coming in later than usual. We care most about hard work and output. We're respectfully opinionated, it will always be us against problems, not each other. Optimize for each other's time and bring solutions, not just problems. You'll join a bench suited to your expertise, but we value cross-domain learning and interoperability across teams.

The office & perks. Waterfront office near Oracle Park, 2x free daily meals, unlimited snacks, company outings most months, and team offsites. Plus a vibrant community: cycling, soccer, figure skating, boxing, run clubs, reading clubs, martial arts, music, game nights.

 

Compensation & Logistics

  • 1099 (or W8-BEN) contract, 40 hrs/week, no end date

  • Fully performance-based pay: $120K–$180K, uncapped upside. 2x quota = 2x pay.

  • 2-4 week paid ramp—full OTE from day one

  • Remote (globally), hybrid, or onsite in SF (onsite preferred)

  • Work authorization: OPT visa holders only (not STEM Extension)

  • Onsite perks: 2x free meals/day, waterfront office (China Basin), monthly parking (based on availability)

  • Candidates with all of the above qualifications + proven management skills will be eligible for more senior positions

     

Interview Process

Timeline: We move fast: 8–12 days from submission to offer.

  1. Intro Screen - Technical Recruiter

  2. Take-Home Project - HackerRank

  3. Technical Interview - Member of Technical Staff

  4. Culture Interview - C-Suite

  5. Offer

How we score this

AI Biologist - Metagenomics at LatchBio scores 83 out of 100 on AI centrality, which makes it AI Level 4 of 4 (Builds AI) on this board. The level measures how much of the work is AI, not seniority.

Classification

AI Level 4. Building AI systems is the job itself: without AI, the role would not exist.

  1. AI Level 480 to 100
  2. AI Level 360 to 79
  3. AI Level 240 to 59
  4. AI Level 10 to 39

Bands come from how often the tools, models and workflows of the role are named in the posting itself. Open the description and count.

Prepare for this job

A free preview built only from this posting: what it asks for, what you could be asked in an interview, and how to adjust your resume.

Skills and AI tools this role asks for

AI Agents

Questions you could be asked

  1. How do you decide when an AI agent can act on its own versus asking for approval first?
  2. How would you decide a model or AI system is ready to ship?
  3. Tell me about a time a model underperformed in production. How did you find out, and what did you change?

Adapt your resume

  • List these exact terms on your resume: AI Agents. An applicant tracking system matches the wording, not the idea.
  • Attach one line of real, concrete experience to at least one of them — a tool named with nothing behind it rarely survives a human read.
  • Lead with what you built, trained or shipped — this role is judged on the AI system itself, not the tools around it.

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