Principal Data Scientist – DDSAI GD

Johnson & Johnson is hiring a Principal Data Scientist – DDSAI GD. It pays $117k-$201k a year and Level rates it ; you can apply on Johnson & Johnson.

Level's read on this job

Level rates this data scientist role Builds AI ●●●●: the job is building AI systems.
Tools and skills the posting cites include Python, R and SQL.
Level classifies it as a lead role.
Level lists 1,800+ other open roles at Johnson & Johnson.
The role was posted within the past week.

AI in this role

Lead end-to-end delivery of machine learning, generative AI, and optimization solutions for clinical development.

pythonrsqlmachine-learninggenai

ml-opsnlpdata-sciencepredictive-modelingclinical-trialsreal-world-dataoptimization

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Data Analytics & Computational Sciences

Job Sub Function:

Data Science

Job Category:

Scientific/Technology

All Job Posting Locations:

Titusville, New Jersey, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

Job Summary

J&J Innovative Medicine – Data, Data Science, and AI - Global Development (DDSAI GD) is seeking a Principal Data Scientist to lead end-to-end delivery of integrated analytical solutions for defined clinical-development and trial-operations business problems. This role owns solution definition, delivery, adoption, and use-case outcomes across connected stakeholder groups using ML, GenAI, optimization, and RWD.

Key Responsibilities

Own the end-to-end definition, development, validation, deployment, and adoption of integrated data-science solutions for defined business problems.
Lead predictive modeling, simulations, optimization, and GenAI applications for study feasibility, enrollment forecasting, country and site selection, protocol design, and operational planning.
Apply clinical, operational, cost, and RWD—including EHR, claims, registries, and clinical-trial data—to generate evidence on patient populations, treatment pathways, feasibility, and operational risks.
Lead RWD analytics that inform protocol feasibility, eligibility criteria, recruitment and retention, study design, comparative evidence, and external-control use cases.
Develop LLM-enabled workflows for information extraction, protocol comparison, data harmonization, clinical-concept interpretation, and targeted workflow automation.
Partner with clinical, operational, technology, and data stakeholders to frame questions, manage trade-offs, and translate outputs into adopted recommendations and measurable use-case outcomes.
Apply model-validation, MLOps, documentation, privacy, data-quality, and responsible-AI standards; contribute reusable code, data assets, and technical patterns.
Communicate methods, model outputs, assumptions, limitations, and decisions clearly to technical and nontechnical audiences.
Mentor junior colleagues and strengthen delivery practices across project teams.

Required Qualifications

Master’s degree in computer science, engineering, biostatistics, health economics, biomedical informatics, applied mathematics, or another quantitative discipline; PhD preferred.
At least 5 years of industry experience leading end-to-end delivery of data-science solutions using ML, predictive modeling, optimization, NLP, GenAI, or RWD analytics.
Demonstrated experience defining, validating, deploying, and driving adoption of analytical solutions that inform clinical-development, clinical-operations, or real-world evidence decisions.
Hands-on experience with structured and unstructured clinical, operational, or RWD data, including multimodal modeling and time-series or simulation methods.
Proficiency in Python and SQL, modern ML, optimization, and LLM-development libraries, and reproducible MLOps practices.
Strong communication, stakeholder-management, and technical-leadership skills.

Preferred Qualifications

Experience in healthcare, pharmaceutical development, MedTech, clinical development, or clinical operations.
Experience applying RWD methods to clinical-trial design, including target-trial emulation, propensity methods, survival analysis, or time-to-event analysis.
Experience delivering analytical products or applications used by clinical or business teams.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource.

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Required Skills:

Preferred Skills:

Advanced Analytics, Coaching, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Organizing, Process Improvements, Strategic Thinking, Technical Credibility, Workflow Analysis

The anticipated base pay range for this position is :

$117,000.00 - $201,250.00

Additional Description for Pay Transparency:

Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).

Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:

Vacation –120 hours per calendar year

Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year

Holiday pay, including Floating Holidays –13 days per calendar year

Work, Personal and Family Time - up to 40 hours per calendar year

Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child

Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year

Caregiver Leave – 80 hours in a 52-week rolling period10 days

Volunteer Leave – 32 hours per calendar year

Military Spouse Time-Off – 80 hours per calendar year

For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits

How we rate this

Principal Data Scientist – DDSAI GD at Johnson & Johnson rates 85 out of 100 for how much of the daily work is AI. That makes it Builds AI (AI Level 4 of 4). The level is about AI in the job, not seniority.

Classification

Builds AI. The job is building AI systems.

●●●● Builds AI80 to 100
●●●○ Works on AI60 to 79
●●○○ Uses AI40 to 59
●○○○ Little AI0 to 39

Levels come from how often the tools, models and workflows of the role are named in the posting itself. Read the description and count the AI tools, models and workflows it names.

Key facts

Principal Data Scientist – DDSAI GD is an open job at Johnson & Johnson.
Level rates this role AI Level 4 of 4: Builds AI.
The listed salary is $117k-$201k a year.
The role is based in Titusville, New Jersey, United States of America.
The job was posted on October 29, 2026.
Seniority: lead.
Applications are handled by Johnson & Johnson. Apply on Johnson & Johnson

Prepare for this job

Built from this posting and from similar jobs on Level.

Skills and AI tools this role asks for

ML OpsNLPData SciencePredictive ModelingClinical TrialsReal World DataOptimizationPython

Also common in data scientist jobs at this level

Machine learning AWS Spark Deep learning PyTorch RAG

Pay

This job starts at: $117k
Typical data scientist job: $166k

This posting starts 29% below the typical data scientist job. See data scientist jobs

Questions you could be asked

How do you monitor a model once it's live, and how do you know it needs retraining?
What NLP problem have you worked on, and how did you measure whether it actually worked?
Tell me about a project where data science was part of your work. What did you do?
Tell me about a project where predictive modeling was part of your work. What did you do?
Tell me about a project where clinical trials was part of your work. What did you do?

Adapt your resume

List these exact terms on your resume: ML Ops, NLP, Data Science, Predictive Modeling, and Clinical Trials. An applicant tracking system matches the wording, not the idea.
Attach one line of real, concrete experience to at least one of them. A tool named with nothing behind it rarely survives a human read.
Lead with what you built, trained or shipped. This role is judged on the AI system itself, not the tools around it.

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