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Senior Scientist / Scientist, Cell-Based Assays & Immunology

Senior Scientist / Scientist, Cell-Based Assays & Immunology at C10 Labs scores 16 out of 100 on AI centrality, which makes it AI Level 1 of 4 (Little AI) on this board. The level measures how much of the work is AI, not seniority.

Cambridge, MassachusettsseniorFull Time

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About Noara Therapeutics 
Noara Therapeutics is an early-stage, stealth biotechnology company developing next-generation RNA-LNP-based cell  therapies for the treatment of autoimmune diseases, cancer, and other chronic conditions. Our platform integrates  synthetic biology, RNA engineering, machine learning, and high-throughput experimentation to create durable, effective  therapies with reduced immunotoxicity. As a growing startup, we offer a collaborative, fast-paced environment where  every team member has a direct impact on scientific strategy and company success. We are seeking a highly motivated  scientist to lead the development and execution of cell-based and immunology assays that will guide therapeutic  discovery and development. 
Position Summary 
We are seeking an experienced Senior Scientist or Scientist with deep expertise in cell biology, immunology, and assay  development. This is a laboratory-based role with significant opportunities to influence experimental strategy, establish  new capabilities, and contribute to the scientific direction of our platform. 
The successful candidate will work closely with colleagues across molecular biology, computational biology, automation,  and data science to develop robust, scalable assays that support discovery and optimization of our therapeutic  candidates. 

What You Will Do

• Design, develop, optimize, and execute cell-based and immunology assays to evaluate candidate potency,  cytotoxicity, and biological activity. • Perform and optimize reporter assays, flow cytometry, and fluorescence-activated cell sorting (FACS) for cellular  characterization and functional assessment. • Culture, engineer, and characterize human primary cells, with particular emphasis on immune cell populations. • Prepare, deliver, and evaluate RNA-LNP formulations in relevant cellular systems. • Develop scalable, plate-based assay workflows suitable for high-throughput experimentation, including assay  miniaturization, troubleshooting, and SOP development. • Collaborate closely with molecular biology, computational biology, machine learning, and automation teams to  generate high-quality datasets for downstream analysis and model development. • Contribute to the establishment of laboratory infrastructure, experimental standards, and best practices. • Mentor junior scientists and foster a collaborative, scientifically rigorous research environment. 

What We Are Looking For

• Ph.D. in Immunology, Cell Biology, Molecular Biology, or a related discipline. • For Scientist candidates: 3+ years of relevant industry experience; biotechnology or startup experience is preferred. • For Senior Scientist candidates: 5+ years of relevant industry experience with demonstrated scientific leadership;  biotechnology or startup experience is preferred. • Demonstrated expertise in designing, developing, and optimizing complex cell-based assays. • Extensive hands-on experience with flow cytometry and FACS, including multicolor panel design and cell sorting. • Strong experience working with human primary cells, particularly primary immune cells. • Experience with RNA-LNP delivery systems and/or engineered cell therapies (including CAR-based platforms or  related technologies).• Proven ability to independently lead assay development from concept through implementation. • Excellent experimental troubleshooting, analytical, and scientific communication skills. • Ability to thrive in a dynamic, fast-paced startup environment where adaptability, initiative, and collaboration are  essential. 

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