Senior ML Systems Engineer, Inference
RunPod is hiring a Senior ML Systems Engineer, Inference for a remote role open to applicants in United States. It pays $150k-$220k a year and Level rates it ; you can apply on RunPod.
Level's read on this job
- On Level's scale, this role is Builds AI ●●●●: the job is building AI systems.
- This is listed as a remote role.
- The posting mentions vLLM, Python and CUDA among its tools and skills.
- Level classes it as a senior role.
- RunPod has 22 other open roles on Level.
AI in this role
Lead LLM inference performance, optimization, and scaling across GPU deployments at Runpod.
Runpod is the AI Developer Cloud. More than one million developers, from indie researchers to teams running frontier models in production, use Runpod to experiment, train, fine-tune, deploy, and scale AI on one platform. The platform has processed more than 20 billion inference requests. We closed a $100M Series A in June 2026. We're at an inflection point for AI infrastructure, and we're building the platform the next generation of developers will depend on.
We're a small, remote-first team. We take ownership seriously, move fast, and ship work that more than a million developers rely on every day. We're looking for people who care deeply, build with urgency, and want to matter at scale.
Learn more in our CEO's funding announcement: https://www.runpod.io/blog/one-million-developers.
We're looking for a ML Systems Engineer, Inference. We want Runpod to be the best place in the world to run LLM inference, meaning the fastest and the most cost-efficient. You'll lead that effort. You'll own LLM serving performance end to end. That means measuring it, understanding it, and improving it across models, hardware generations, and workloads. The work you ship will show up directly in the latency and cost our customers experience. This is a hands-on engineering role for someone who likes finding the real bottleneck and fixing it, then turning that fix into something that runs reliably in production.
Responsibilities
Define how we measure inference performance, including throughput, time to first token, inter-token latency, and cost per token, and build the tooling that makes those measurements rigorous and repeatable.
Profile and diagnose performance problems across the serving stack, from scheduling and memory management down to kernels and interconnect.
Improve serving efficiency for large, state-of-the-art models on single-node and multi-node GPU deployments.
Turn what you learn into production-ready runtimes, configurations, and defaults that customers benefit from automatically.
Work closely with product and infrastructure teams to shape how inference is offered on Runpod.
Keep up with the fast-moving inference ecosystem, including the open-source community, and decide what's worth adopting, what's worth building, and what's worth contributing back.
Trace bottlenecks in the serving engine/runtime and implement fixes when configuration tuning is not enough.
Requirements
5+ years of professional system engineering experience.
Deep, hands-on experience with vLLM, SGLang (or a comparable serving engine) in production or at serious benchmark scale.a
Strong software engineering skills in Python. You're comfortable working in large, performance-critical codebases.
A solid understanding of what drives LLM inference performance: batching, memory, parallelism, and the trade-offs between latency and throughput.
Experience with modern inference optimization techniques such as quantization, speculative decoding, or distributed serving.
Rigor in benchmarking and performance analysis, plus comfort with GPU profiling tools.
The ability to explain your results clearly in writing and turn them into decisions.
Preferred
Experience writing or tuning GPU kernels in CUDA or Triton.
Contributions to inference or ML systems projects.
Experience with multi-node GPU systems and high-speed networking.
Experience at a company where inference cost and latency were core business metrics.
What You’ll Receive:
The competitive base pay for this position ranges from ($150,000 - $220,000). This salary range may be inclusive of several career levels at Runpod and will be narrowed during the interview process based on a number of factors, including the candidate’s experience, qualifications, and location
Meaningful equity in a fast-growing company- everyone on the team receives stock options — your impact drives our growth, and you share in the upside.
Generous medical, dental & vision plans
Flexible PTO- take the time you need to recharge
Most roles are remote work first with an inclusive, collaborative teams utilizing slack as the main form of internal communication
Join a passionate team on the cutting edge of AI infrastructure — where culture, learning, and ownership are at the heart of how we scale.
$1,200 Home Office & Equipment Stipend- We set you up for success from day one with gear and support to create your ideal workspace
Runpod is committed to maintaining a workplace free from discrimination and upholding the principles of equality and respect for all individuals. We believe that diversity in all its forms enhances our team. As an equal opportunity employer, Runpod is committed to creating an inclusive workforce at every level. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, marital status, protected veteran status, disability status, or any other characteristic protected by law. We welcome every qualified candidate eligible to work in the United States; however, we are currently unable to sponsor employment visas.
How we rate this
Senior ML Systems Engineer, Inference at RunPod rates 90 out of 100 for how much of the daily work is AI. That makes it Builds AI (AI Level 4 of 4). The level is about AI in the job, not seniority.
Builds AI. The job is building AI systems.
- ●●●● Builds AI80 to 100
- ●●●○ Works on AI60 to 79
- ●●○○ Uses AI40 to 59
- ●○○○ Little AI0 to 39
Levels come from how often the tools, models and workflows of the role are named in the posting itself. Read the description and count the AI tools, models and workflows it names.
Prepare for this job
Built from this posting and from similar jobs on Level.
Skills and AI tools this role asks for
Questions you could be asked
- Tell me about a project where llm inference was part of your work. What did you do?
- Tell me about a project where performance profiling was part of your work. What did you do?
- Tell me about a project where gpu optimization was part of your work. What did you do?
- Tell me about a project where distributed systems was part of your work. What did you do?
- Walk me through how you've used vLLM in your day-to-day work.
Adapt your resume
- List these exact terms on your resume: LLM Inference, Performance Profiling, GPU Optimization, Distributed Systems, and vLLM. An applicant tracking system matches the wording, not the idea.
- Attach one line of real, concrete experience to at least one of them. A tool named with nothing behind it rarely survives a human read.
- Lead with what you built, trained or shipped. This role is judged on the AI system itself, not the tools around it.
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